Results 181 to 190 of about 909,616 (291)
تهدف التربية الصحية إلى دفع الناس من جميع الاعمار إلى تحمل المسؤولية فيما يتعلق بصحتهم الشخصية. وبهذا فإن الهدف يتمثل في التحلل من انماط السلوك الخطر وبناء انماط سلوك صحي بما في ذلك الاحتفاظ بأنماط السلوك التي تم اكتسابها والتي هي داعمة للصحة. وتتميز هذه العملية بصعوبات كثيرة ولا تحقق على ما يبدو، لدى المعنيين، النجاح المرغوب. فقد ظهر أن كثيرا من انماط
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People value solitude in varying degrees. Theories and studies suggest that people’s appreciation of solitude varies considerably across persons (e.g., an introverted person may value solitude more than an extraverted person), and solitude experiences (i.e., on average, people may value some functions of solitude, e.g., privacy, more than other ...
Dongning Ren +3 more
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Cancer stem cells (CSCs) in non‐small cell lung cancer display pronounced plasticity and spatial heterogeneity. By integrating single‐cell and spatial transcriptomics, this study defines a DSG2‐associated CSC program and reveals a tumor‐margin niche formed with FAP+ myofibroblasts.
Guangyu Fan +8 more
wiley +1 more source
Risk factors for the mental health of basic education teachers in Brazil: integrative review. [PDF]
da Costa ACS +3 more
europepmc +1 more source
يتيح توفر أدوات القياس المقننة على البيئة المحلية والبيئات الأخرى إجراء تشخيص دقيق للاضطرابات النفسية و تنفيذ دراسات مسحية ومقارنة، وعلى الأخص فيما يتعلق بواحد من أكثر الاضطرابات النفسية شيوعاً، ألا وهو الاكتئاب. وقد هدفت هذه الدراسة إلى تقنين قائمة بيك للاكتئاب التي تعتبر واحدة من أكثر الأدوات انتشاراً واستخداماً في العالم.
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Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation
Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong +13 more
wiley +1 more source
Prevalence and factors associated with the use of benzodiazepines among teachers in Espírito Santo: a cross-sectional study. [PDF]
Mazzini YC +6 more
europepmc +1 more source
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin +12 more
wiley +1 more source
Reconfiguration of life and work routines of senior professors during the COVID-19 pandemic. [PDF]
Rocha BDAC, Tura LFR, Ferreira MA.
europepmc +1 more source
Low Back Pain in Medical Students and Professors During the Pandemic: Retrospective Cohort Study. [PDF]
Mattos AF +3 more
europepmc +1 more source

