Results 151 to 160 of about 36,514 (265)

Prevalence and factors associated with the use of benzodiazepines among teachers in Espírito Santo: a cross-sectional study. [PDF]

Rev Bras Epidemiol
Mazzini YC, Antonucci BL, Pereira GR, Reis WCT, Rocha KSS, Faro A, Araújo DCSA.   +6 more
europepmc   +1 more source

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

Advanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu, Ci‐ming Sun, Sui‐xian Zhang, Rui Li, Chen‐fei Wu, Zai‐shan Lin, Li Li, Run‐zhe Chen, Qi‐wen Li, Yuan‐yuan Chen, Xuan Li, Ming Chen   +11 more
wiley   +1 more source

Risk factors for the mental health of basic education teachers in Brazil: integrative review. [PDF]

Rev Bras Med Trab
da Costa ACS, de Souza EA, Daniele TMDC, Frota MA.   +3 more
europepmc   +1 more source

Tailored D‐π Conjugation Boosts Piezocatalytic CO2 Reduction in a Platinum(II)‐Acetylide Framework

Advanced Science, EarlyView.
The highly conjugated metalII‐acetylide framework demonstrates efficient ultrasound‐driven conversion of CO2 to CO. The piezoelectric field generated by ultrasound facilitates electron transfer from the tetraphenylene π‐column to the MII‐bis(acetylide) moiety, enabling CO2 activation. Compared to PdII‐ and NiII‐based analogues, the stronger d–π orbital
Mude Zhu, Yingtang Zhou, Kai Wang, Xiaoyun Fan, Yang Ding, Wai‐Yeung Wong, Linli Xu   +6 more
wiley   +1 more source

Self-perception of vocal fatigue and insomnia severity in teachers. [PDF]

Codas
Nascimento JLAD, Araujo FS, Ribeiro VV, Godoy JF, Siqueira LTD.   +4 more
europepmc   +1 more source

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

Advanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu, Huan Liu, Songyin Zhao, Lei Qin, Jiarui Li, Jun Wang, Zixuan Dai, Jie Gu, Yan Xu, Feiran Li, Yao Nie   +10 more
wiley   +1 more source

Reconfiguration of life and work routines of senior professors during the COVID-19 pandemic. [PDF]

Rev Bras Enferm
Rocha BDAC, Tura LFR, Ferreira MA.
europepmc   +1 more source

التعصب التحليل النفسي لظاهرة مرعبة assistant Professor associate Professor Professor associate Professor Professor

زعزع اعتداء 11 سبتمبر عالم 2001 الوهم المتمثل في أنه في عالم الغد التقني-العقلاني سوف يصبح الحقد التعصبي في عالم الغد التقني-العقلاني عاملاً محسوباً. فمن تفاعل ذهنية متطرفة و أسلحة التدمير الشامل انبثقت سيناريوهات تهديد غير متوقعة. و تبدو اليوم المعالجة الجذرية لجوهر الفكر التعصبي أكثر إلحاحاً من أي وقت مضى.
openaire   +1 more source

The Policy Relevance of Personality Traits Professor Professor Professor

Personality traits are powerful predictors of outcomes in the domains of education, work, relationships, health, and well-being. The recognized importance of personality traits has raised questions about their policy relevance – that is, their potential to inform policy actions designed to improve human welfare.
Wiebke Bleidorn, Patrick Hill, Mitja Back, Jaap Denissen, Marie Hennecke, Chris Hopwood, Markus Jokela, Christian Kandler, Richard E. Lucas, Maike Luhmann   +9 more
openaire   +1 more source

Aromaticity‐Engineered Open‐Shell Radical Anions for Air‐Stable Doublet Emission in N‐Annulated Perylene Diimide

Advanced Science, EarlyView.
Open‐shell type radical anions with stable doublet emission have been synthesized that feature aromaticity engineering, through‐space charge‐transfer (TSCT), and electro(fluoro)chromism. ABSTRACT We report the doublet emissive open‐shell radical anions, where the N‐annulated perylene diimide (PDIN–H) is functionalized with aromatic rings.
Jeongyoon Kim, Soyoon Lee, Min‐Ji Kim, Mina Ahn, Kyung‐Ryang Wee   +4 more
wiley   +1 more source