Results 261 to 270 of about 312,430 (306)

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source

The modernization of medical training at Escola Paulista de Medicina and the Rockefeller Foundation, 1956-1962. [PDF]

Hist Cienc Saude Manguinhos
Batista RDS.
europepmc   +1 more source

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source

Understanding how interculturality is taught and learned by students, professors, and academic authorities through phenomenography. [PDF]

Rev Esc Enferm USP
Acuña CVP, Medina JL.
europepmc   +1 more source

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

Impacts of the COVID-19 pandemic on the health of university teachers and students: a scoping review. [PDF]

Front Psychol
Guimarães de Araujo Faria M, da Silva Freitas Venâncio CG, Carvalho Pacheco F, Ferreira Koopmans F, Valadão Vasconcelos Alves L, Maia Valente P.   +5 more
europepmc   +1 more source

Terahertz Channel Modeling, Estimation and Localization in RIS‐Assisted Systems

Advanced Electronic Materials, EarlyView.
Reconfigurable intelligent surfaces have become a recent intensive research focus. Based on practical applications, channel strategies for RIS‐assisted terahertz wireless communication systems are categorized into three different types: channel modeling, channel estimation, and channel localization.
Hongjing Wang, Weipeng Wang, Xuan Cong, Shiyu Wang, Gao Li, Sen Gong, Lin Huang, Hongxin Zeng, Yaxin Zhang, Ziqiang Yang   +9 more
wiley   +1 more source

Exceptional Antimodes in Multi‐Drive Cavity Magnonics

Advanced Electronic Materials, EarlyView.
Driven‐dissipative cavity‐magnonics provides a flexible platform for engineering non‐Hermitian physics such as exceptional points. Here, using a four‐port, three‐mode system with controllable microwave interference, antimodes and coherent perfect extinction (CPE) are realized, enabling active tuning to antimode exceptional points.
Mawgan A. Smith, Ryan D. McKenzie, Alban Joseph, Robert L. Stamps, Rair Macêdo   +4 more
wiley   +1 more source

Beyond the Gold Standard: Towards Industrially Viable Electrodes for Durable Perovskite Solar Cells

Advanced Energy Materials, EarlyView.
Transparent and opaque electrode materials are mapped by raw material cost per 1 m2 electrode area and retained median device efficiency after heat–light ageing. FTO offers a lower‐cost and more stable alternative to ITO, while Cr/Al provides the lowest‐cost rear electrode investigated with Au‐like stability and substantially improved durability ...
Tino Lukas, Manuel Kober‐Czerny, Ali Reza Nazari Pour, James McGettrick, Georgios Loukeris, Clemens Baretzky, Shuaifeng Hu, Junke Wang, Chia‐Yu Chang, Sam Teale, Bowei Li, Trystan M. Watson, Martin Stolterfoht, Robert L. Z. Hoye, Philippe Holzhey, Lukas Wagner, Markus Kohlstädt, Henry J. Snaith   +17 more
wiley   +1 more source

Synergistic Anode Engineering for Aqueous Aluminium Ion Batteries: From Mechanistic Understanding to Computationally Accelerated Design

Advanced Energy Materials, EarlyView.
Mechanistic anode engineering for aqueous aluminium‐ion batteries is discussed through alloying and microstructure control, surface/interface engineering, and electrolyte modification to regulate ion transport, suppress dendrites, passivation, hydrogen evolution, and side reactions, highlighting standardisation, computational acceleration, and ...
Hong Zhao, Ting Liu, Lianzhou Wang, Matthew Dargusch   +3 more
wiley   +1 more source