Results 121 to 130 of about 36,722 (265)

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

Advanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu, Huan Liu, Songyin Zhao, Lei Qin, Jiarui Li, Jun Wang, Zixuan Dai, Jie Gu, Yan Xu, Feiran Li, Yao Nie   +10 more
wiley   +1 more source

The Professor Is In

The Canadian Journal of Hospital Pharmacy, 2009
openaire   +3 more sources

Open System Model of Choice and Response Time Professor Professor Professor Assistant/Associate Professor Professor

Sequential sampling models have provided accurate accounts of people’s choice, response time, and preference strength in value-based decision-making tasks. Conventionally, these models are developed as Markov-type processes (such as random walks or diffusion processes) following the Kolmogorov axioms.
Gunnar Epping, Peter Kvam, Tim Pleskac, Jerome R Busemeyer   +3 more
openaire   +1 more source

Aromaticity‐Engineered Open‐Shell Radical Anions for Air‐Stable Doublet Emission in N‐Annulated Perylene Diimide

Advanced Science, EarlyView.
Open‐shell type radical anions with stable doublet emission have been synthesized that feature aromaticity engineering, through‐space charge‐transfer (TSCT), and electro(fluoro)chromism. ABSTRACT We report the doublet emissive open‐shell radical anions, where the N‐annulated perylene diimide (PDIN–H) is functionalized with aromatic rings.
Jeongyoon Kim, Soyoon Lee, Min‐Ji Kim, Mina Ahn, Kyung‐Ryang Wee   +4 more
wiley   +1 more source

Giant Bulk Photovoltaic Effect in Two‐Dimensional Topological Ferroelectric Semimetal

Advanced Science, EarlyView.
ABSTRACT Ferroelectric (FE) metals have attracted growing interest because they combine ferroelectricity with metallic behavior and enable polarization‐controlled band topology near the Fermi level. However, the number of known ferroelectric metals is still limited.
Jianhua Wang, Xia Cheng, Shibo Fang, Tao Zhu, Xiaodong Zhou, Shifeng Qian, Tie Yang, Wenhong Wang, Yee Sin Ang   +8 more
wiley   +1 more source

Apresentação

Convergência Lusíada, 2017
O número 28 da revista Convergência Lusíada apresenta ao leitor um conjunto heterogêneo de textos sobre autores de diferentes épocas e gêneros, de autoria de pesquisadores brasileiros e portugueses. [...]
Madalena Vaz Pinto
doaj  

Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing

Advanced Science, EarlyView.
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma, Pengcheng Yao, Shengqi Wu, Yuanyuan Shi, Lang Qin, Baitao Li, Jiayi Zhu, Minhua Huang, Yichong Zhu, Yuwen Song, Jinhuan Pang, Ziping Guo, Guochuan Wu, Chen Wang, Kewei Xu, Ruihua Huang, Quan Kuang, Liang Qu, Changtian Pan, Xianrong Xie, Qinlong Zhu, Jiaying Huang, Qiupeng Lin   +22 more
wiley   +1 more source

Validation of the Central Auditory Processing Self-Perception Questionnaire (QAPAC) applied to students, parents, and teachers. [PDF]

Codas
Tambascia BL, Carvalho NG, Colella-Santos MF, Amaral MIRD.   +3 more
europepmc   +1 more source

الفصام: أسبابه وعلاجه Editor of ArabiXiv assistant Professor associate Professor Professor associate Professor Professor

يعني مفهوم الفصام "انقسام العقل أو الشخصية" حيث يشعر المريض وكأن ذاته وأحاسيسه وإدركاته منقسمة. وهو من الأمراض التي تصنف ضمن طائفة الذهانات داخلية المنشأ، أي الذهانات التي لا تزال أسباب ظهورها غامضة. وهذا الاضطراب يعيق الوظائف الأساسية التي تمنح الإنسان السوي مشاعر الفردية والخصوصية وحرية الاختيار، وغالباً ما يعتقد الفصامي أن أفكاره ومشاعره العميقة ...
Khaled Moustafa, Samer Rudwan
openaire   +1 more source

Machine Learning Accelerated Non‐Adiabatic Molecular Dynamics Elucidates Local Polarization Effects on Non‐radiative Recombination in Halide Perovskites

Advanced Science, EarlyView.
This work proposes and constructs the Hefei‐NAMD‐S framework based on machine learning stacked models to investigate the relationship between local polarization and non‐radiative recombination. The results indicate that, compared with A‐site local polarization, B‐site local polarization shows a more evident association with the non‐radiative ...
Bing Yang, Xiaoli Wei, Bo Cai, Yan Yang, Xinghai Zhu, Yi Liu, Junmin Xia, Lihui Liu, Kun Cao, Wei Shen, Pengfei Xia, Shufen Chen, Siyu Chen, Jin Zhao   +13 more
wiley   +1 more source