Results 141 to 150 of about 36,224 (265)

Prevalence and factors associated with the use of benzodiazepines among teachers in Espírito Santo: a cross-sectional study. [PDF]

Rev Bras Epidemiol
Mazzini YC, Antonucci BL, Pereira GR, Reis WCT, Rocha KSS, Faro A, Araújo DCSA.   +6 more
europepmc   +1 more source

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

Advanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun, Jianbo Liu, Shi‐Jia Xu, Meng‐Xin Wang, Hongliang Zhang, Yanhe Zhang, Zhi‐Jun Tian, Jin‐Mei Peng, Xin Yin, Tong‐Qing An, Xue‐Hui Cai, Yan‐Dong Tang   +11 more
wiley   +1 more source

Risk factors for the mental health of basic education teachers in Brazil: integrative review. [PDF]

Rev Bras Med Trab
da Costa ACS, de Souza EA, Daniele TMDC, Frota MA.   +3 more
europepmc   +1 more source

Stretchable Microelectrode Arrays with Microneedles for Reliable Electrophysiological Recording of Human Heart and Brain Organoids

Advanced Science, EarlyView.
A stretchable 3D microelectrode array with microneedles (3D MN‐sMEA) enables stable, minimally destructive electrophysiological monitoring of 3D organoids. The wafer‐level stud‐bump bonding process facilitates high‐fidelity recordings of heart and cerebral organoids.
Eunyoung Jang, Saewoon Shin, Seul‐Gi Lee, Kiup Kim, Yoojeong Kim, Jun Sun, Il‐Joo Cho, Joseph A. Gogos, Jong‐Chan Park, C‐Yoon Kim, Hyunjoo J. Lee   +10 more
wiley   +1 more source

Self-perception of vocal fatigue and insomnia severity in teachers. [PDF]

Codas
Nascimento JLAD, Araujo FS, Ribeiro VV, Godoy JF, Siqueira LTD.   +4 more
europepmc   +1 more source

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, EarlyView.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

Reconfiguration of life and work routines of senior professors during the COVID-19 pandemic. [PDF]

Rev Bras Enferm
Rocha BDAC, Tura LFR, Ferreira MA.
europepmc   +1 more source

التعصب التحليل النفسي لظاهرة مرعبة assistant Professor associate Professor Professor associate Professor Professor

زعزع اعتداء 11 سبتمبر عالم 2001 الوهم المتمثل في أنه في عالم الغد التقني-العقلاني سوف يصبح الحقد التعصبي في عالم الغد التقني-العقلاني عاملاً محسوباً. فمن تفاعل ذهنية متطرفة و أسلحة التدمير الشامل انبثقت سيناريوهات تهديد غير متوقعة. و تبدو اليوم المعالجة الجذرية لجوهر الفكر التعصبي أكثر إلحاحاً من أي وقت مضى.
openaire   +1 more source

The Policy Relevance of Personality Traits Professor Professor Professor

Personality traits are powerful predictors of outcomes in the domains of education, work, relationships, health, and well-being. The recognized importance of personality traits has raised questions about their policy relevance – that is, their potential to inform policy actions designed to improve human welfare.
Wiebke Bleidorn, Patrick Hill, Mitja Back, Jaap Denissen, Marie Hennecke, Chris Hopwood, Markus Jokela, Christian Kandler, Richard E. Lucas, Maike Luhmann   +9 more
openaire   +1 more source

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

Advanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu, Ci‐ming Sun, Sui‐xian Zhang, Rui Li, Chen‐fei Wu, Zai‐shan Lin, Li Li, Run‐zhe Chen, Qi‐wen Li, Yuan‐yuan Chen, Xuan Li, Ming Chen   +11 more
wiley   +1 more source