Results 41 to 50 of about 227,658 (256)

Cultural Intelligence and Its Relation to Sustainable Management Behaviors among Head Nurses [PDF]

open access: yesInternational Egyptian Journal of Nursing Sciences and Research
Background: Cultural intelligence enables head nurses to navigate cultural differences, which not only improves team cohesion and staff well-being but also enriches the delivery of patient care and subsidizes the sustainable management of healthcare ...
Aya Ghoneimy, Amira Abd El-Moneim
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

CNS toxoplasmosis in an immunocompetent individual

open access: yesRadiology Case Reports, 2014
Toxoplasmosis is a serious and life-threatening disease in humans with a high prevalence in immunocompromised persons. The disease has a wide spectrum, depending on the immune status of the person.
Rajoo Ramachandran, MBBS, MD   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The Role of Hillshade, Aspect, and Toposhape in the Woodland Dieback of Arid and Semi-Arid Ecosystems: A Case Study in Zagros Woodlands of Ilam Province, Iran

open access: yesJournal of Landscape Ecology, 2019
Soil moisture plays a key role in the ecological capability of arid and semi-arid woodland. Reducing soil moisture due to frequent droughts causes pest prevalence and disease outbreak and the consequence of forest dieback.
Najafifar Ali   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Supply chain inefficiencies: the causes and costs of dry bulk ships anchored in Vancouver

open access: yesJournal of Shipping and Trade
The paper describes the contracting and logistics conditions contributing to the level of anchorage in the grain, coal and fertiliser export trades of Vancouver. Increases in the level of anchorage in these trades have created economic, environmental and
Trevor Heaver, Derek Atkins
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy