Results 171 to 180 of about 7,101,969 (301)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Foreign-Trained Dentists' Experiences of the Swedish Proficiency Test for Recognition of Dental Qualifications. [PDF]

Eur J Dent Educ
Dalum J, Brodén J, Johannsen A, Sandborgh-Englund G.   +3 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

9th Grade Math Proficiency Test

9th Grade Math Practice Questions to test addition, multiplication, word-problem skills, and basic algebraic skills. Includes answers and explanations.

core  

Highlighting the Importance of Authentic Reference Chemicals in the Unambiguous Identification of Unknowns during Routine Sample Analysis─An OPCW Proficiency Test Case. [PDF]

J Am Soc Mass Spectrom
Koester CJ, Alfaro TM, Cho DS, Corzett TH, Dreyer ML, Hok S, Kaseman DC, Panasci-Nott AF, Vu AK, Alcaraz A, Valdez CA.   +10 more
europepmc   +1 more source

Gen-FS coordinated proficiency test data for genomic foodborne pathogen surveillance, 2017 and 2018 exercises. [PDF]

Sci Data, 2020
Timme RE, Lafon PC, Balkey M, Adams JK, Wagner D, Carleton H, Strain E, Hoffmann M, Sabol A, Rand H, Lindsey R, Sheehan D, Baugher JD, Trees E.   +13 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

External quality assessment for yaws elimination in low- and middle-income countries using plasmid-based proficiency test items. [PDF]

PLoS Negl Trop Dis
Mueller C, Tchatchouang S, Basing LA, Ngazoa-Kakou S, Hugues KA, Handley BL, Beiras CG, Amanor IB, Ndzomo P, Bakheit MA, Becherer L, Tabah EN, Crucitti T, Borst N, Ries C, Lueert S, Frischmann S, Gmoser H, Landmann E, Sylla A, Kouamé-Sina SM, Arhinful D, Awondo P, Burl S, Harding-Esch EM, Tano A, Mitjà O, Eyangoh S, Addo KK, Marks M, Knauf S.   +30 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Correlation between physical fitness, psychophysiological parameters and performance in a firearm proficiency test in military police officers. [PDF]

Front Psychol
Junger AF, de Oliveira GS, Viana MV, Pinheiro MA, Junior PFDCF, Rica RL, Bullo V, Gobbo S, Bergamin M, Bocalini DS.   +9 more
europepmc   +1 more source