Results 131 to 140 of about 333,801 (297)
Modified Profile Likelihood Approach for Certain Intraclass Correlation Coefficient
, 2011 In this paper we consider the problem of constructing confidence intervals and lower bounds forthe intraclass correlation coefficient in an interrater reliability study where the raters are randomly selected from a population of raters.The likelihood ...
Liu, Huayu
core +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Hierarchical Generalized Linear Models: The R Package HGLMMM
Journal of Statistical Software, 2011 The R package HGLMMM has been developed to fit generalized linear models with random effects using the h-likelihood approach. The response variable is allowed to follow a binomial, Poisson, Gaussian or gamma distribution.
Marek Molas, Emmanuel Lesaffre
doaj
A robust adjustment of the profile likelihood
The Annals of Statistics, 1996 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
On interval and point estimators based on a penalization of the modified profile likelihood [PDF]
, 2011 Various modifications of the profile likelihood have been proposed in the literature. Despite modified profile likelihood methods have better properties than those based on the profile likelihood, the signed likelihood ratio statistic based on the ...
Ventura, Laura +2 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Profile Likelihood Method in Animal Breeding
, 2002 Varyans unsurları ve bunların fonksiyonlarına hayvan ıslahı uygulamalarında doğrudan ilgi duyulur. Bundan dolayı, bunlar hakkında yorumlamalar yapabilmek önem arzetmektedir.
Fırat, Mehmet Ziya
core
Nuisance parameters, modified profile likelihood and Jacobian prior [PDF]
In a model with nuisance parameters, the maximum likelihood estimators (MLE) of the parameters of interest can be biased. One can reduce the bias due to the presence of the nuisance parameters by removing the O(1) bias of the profile likelihood score. To
Leon-Gonzalez, Roberto, Li, Guangjie
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Efficiency of profile likelihood in semi-parametric models
Semi-parametric model, Profile likelihood, Two-phase outcome-dependent sampling, Efficiency, M-estimator, Maximum likelihood estimator, Efficient score, Efficient information bound,
Yuichi Hirose
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