Results 141 to 150 of about 482,381 (267)

ANALYSIS OF TOоTH PROFILE AND MESHING CHARACTERISTICS OF DOUBLE CYCLOID PIN GEAR TRANSMISSION

Jixie qiangdu
The double cycloid tooth profile was applied to the NN type planetary gear transmission with small tooth difference. By analyzing the concavity, curvature and radius of curvature of the inner and outer cycloid tooth profile, the characteristics of the ...
CUI JianKun, DING JiaLe, SHI YuHeng, ZHANG DeQi   +3 more
doaj  

Letter to the editor response for: "Schneider LS, Kennedy RE, Cutter G. Caution in interpreting disease-modification claims with lecanemab: selective reporting and causal inference. Alzheimer's & Dementia. 2026". [PDF]

Alzheimers Dement
van Dyck CH.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Redirection and reshaping of intense extreme-ultraviolet radiation. [PDF]

Sci Adv
He Y, Magunia A, Mandal H, Mourtada MA, Kleine C, Saha A, Rebholz M, Borisova GD, Hedewig L, Lindenblatt H, Trost F, Frühling U, Papadopoulou CC, Appi E, Düsterer S, Lang T, Alisauskas S, Heyl CM, Palutke S, Braune M, Bömer C, Krebs D, Vinci D, Mosel P, Biesterfeld P, Hartl I, Moshammer R, Kovacev M, Ueda K, Gaarde MB, Ott C, Pfeifer T.   +31 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Effectiveness of Intra-oral Non-skeletally Anchored Appliances in the Correction of Skeletal Class III Malocclusion in Growing Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Cureus
Kourbaj YM, Hajeer MY, Kara-Boulad JM, Zakaria AS, Abou Nassar JN, Alfailany DT, Alam MK.   +6 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

The role of Lagrangian drift in the generation of surface waves by wind. [PDF]

J Fluid Mech
Seitz LR, Freilich MA, Pizzo N.
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Controlling the Diffusion Profile in the Vapor Phase Deposition of Silanes for Gradient Fabrication. [PDF]

Langmuir
Chakraborty S, Young A, Al Macktuf MA, Rutan SC, Collinson MM.   +4 more
europepmc   +1 more source