Results 121 to 130 of about 1,311,331 (302)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Study on Contact Force and Transmission Accuracy of Cycloidal Wheel with Exponential Modification
Jixie chuandong, 2020 RV reducer plays a dominant role in the field of robots because of its advantages of high accuracy，high efficiency and small size.Cycloid wheel，as the key component of RV reducer，directly affects the performance of the transmission system of RV reducer ...
Chen Xinwen, Zhu Min, Wang Qiliang
doaj
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Reverse Active Modification Method of Tooth Profile for RV Reducer Cycloidal Gear
Jixie chuandong, 2019 Tooth profile modification design is a key link in the design and manufacture of cycloidal gear of RV reducer. However, the influence relation of tooth profile error and motion accuracy on tooth profile shape has not been considered in the current design
Xiaotao An +4 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Jixie chuandong, 2011 Parameterized mathematical modeling of gear is established and computation and analysis of the temperature of tooth surface are carried by ANSYS software.The profile modification of involute gear is introduced and the temperature of tooth surface after ...
杨龙, 李应生, 王志强, 汤鱼
doaj
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
PROFILE MODIFICATION INFLUENCE ON THE CONTACT RATIO FOR STRAIGHT BEVEL GEAR
Journal of Industrial Design and Engineering Graphics, 2007 Bevel gear, as octoidal gear, is not accurate involute. As a result, unlike involute cylindrical gear, bevel gear is accomplished by using profile which are not modification or profile with zero modification.
VELICU Doru, MOLDOVEAN Gheorghe
doaj
Modification of the background flow by roll vortices [PDF]
Use of observed wind profiles, such as those obtained from ascent or descent aircraft soundings, for the identification of the expected roll modes is hindered by the fact that these modes are able to modify the wind profiles.
Haack, Tracy, Shirer, Hampton N.
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source