Results 101 to 110 of about 2,987,246 (293)

Design and Research of Slotting Modification Profile for High-Speed and Heavy-Loading Marine Gear

, 2011
According to the requirements of dynamic design for high-speed and heavy-loading marine gear, in view of slotting processing advantages, modification profile slotting cutter used to achieve modify high-speed and heavy-loading marine gear, and the ...
Cong Gui Chen, Yao Bin Hu, Feng Wei Yuan, Liang Bin Hu   +3 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Study on the Precise Modeling Method of Helical Gear with Deviation and Modification

Jixie chuandong, 2018
According to the forming process principle,the influence of the tooth profile modification,helix modification and tooth profile deviation,helix deviation and eccentricity tolerance of radial run-out of the involute helical gear on tooth profile shape is ...
Yuan Yongchao, Liu Zhongming, Mao Jizhe, Cao Yanjun, Zhang Kun   +4 more
doaj  

Methods Development for Protein and Modifications Profiling

, 2021
Post-translational modifications (PTMs) occur in many forms, and broadly influence protein behavior. High-resolution tandem mass spectrometry coupled with engines for the identification of unspecified PTMs, is a first-choice method for their global mapping.
Smiljanić, Katarina, Đukić, Teodora, Vasović, Tamara, Prodić, Ivana, Jovanović, Vesna B., Ćirković Veličković, Tanja   +5 more
openaire   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Study on Contact Force and Transmission Accuracy of Cycloidal Wheel with Exponential Modification

Jixie chuandong, 2020
RV reducer plays a dominant role in the field of robots because of its advantages of high accuracy，high efficiency and small size.Cycloid wheel，as the key component of RV reducer，directly affects the performance of the transmission system of RV reducer ...
Chen Xinwen, Zhu Min, Wang Qiliang
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

齿廓修形对齿轮齿面温度影响分析

Jixie chuandong, 2011
Parameterized mathematical modeling of gear is established and computation and analysis of the temperature of tooth surface are carried by ANSYS software.The profile modification of involute gear is introduced and the temperature of tooth surface after ...
杨龙, 李应生, 王志强, 汤鱼
doaj