Results 101 to 110 of about 497,791 (305)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Design Technique Research of Fine-Forged Spur Bevel Gear Tooth Profile Modification
, 2010 Gear tooth profile modification can be featured to improve working stability of gear equipments, abate noise and vibration, enhance loading ability and prolong usage life of the gears.
Huan Yong Cui +2 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Transmission error in spur gears: Static and dynamic finite-element modeling and design optimization
, 2010 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 07/10/2010.The gear noise problem that widely occurs in power transmission systems is typically characterised by one or more high amplitude acoustic ...
Tharmakulasingam, Raul
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
PROFILE MODIFICATION OF SMALL-PITCH INVOLUTE SPUR GEAR WHEELS
, 1996 There the making methods of involute small-pitch modified wheels by means of tools whose bases are the helical surfaces have been studied. The purposes are to develop and to study the achievement methods of profile modification of teeth along their all ...
Medunetsky, Victor Mikhailovich
core
A Comparison of Polymer Flooding With In-Depth Profile Modification
, 2011 For stratified reservoirs with free crossflow and where fractures do not cause severe channeling, improved sweep is often needed after water breakthrough. For moderately viscous oils, polymer flooding is an option for this type of reservoir.
Olatokunbo O. Akanni +3 more
core +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source