Results 91 to 100 of about 2,987,246 (293)

Theoretical Research of the Modification of Cycloidal Gear used in RV Reducer of Robot

Jixie chuandong, 2015
Aiming at the cycloidal gear used in RV reducer of robots,based on the concept of the single tooth without side clearance,the tooth surface equation of the cycloidal gear after modification is deduced by directly adding the second- order parabolic ...
Zhao Bo, Deng Xiaozhong, Li Tianxing, Su Jianxin   +3 more
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Modification of the carbohydrate profile of oatmeal cookies

BIO Web of Conferences
Excessive sugar consumption worldwide has become an increasing problem in recent years. Excessive sugar consumption can lead to serious diseases such as diabetes and obesity. Confectionery products make a significant contribution to this problem. The carbohydrates in the formulation of traditional confectionery products have a high glycemic index ...
Tkeshelashvili Manana, Bobozhonova Galina, Leonova Irina   +2 more
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Profile Modification of Helical Gear Teeth

Bulletin of JSME, 1966
Few investigations are available concerning the profile modification of helical gear teeth and there are many important problems which should be clarified. The object of the present investigation is to find out the effect of the profile modification on the dynamic properties of helical gears, and furthermore to derive the method for determining the ...
openaire   +2 more sources

Modification of Top Profile with Trigonometric Curve for Scroll Compressor

, 2004
In this study, the geometry theory of top profile with trigonometric curve was presented based on research on the engaging principle of scroll compressors. General modification equations were given and various modifying patterns were discussed.
刘振全, 刘涛
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Cycloid Gear Profile Modification based on Elliptical Method

, 2019
In order to get a more ideal cycloidal profile,a new cycloid profile modification method is proposed. Under the circumstance of keeping the short coefficient and the eccentricity constant,the contour line of the modified tooth profile is obtained by the ...
Wang Quan, Chen Zhilong, Wang Jun, Zhao Daxing, Qin Zhengzheng   +4 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

直齿圆柱齿轮齿廓修行曲线优化设计

Jixie chuandong, 2010
The tooth profile modification can generally choose straight line modification and parabolic modification.Different modification curves have different modification parameters.In order to accurately determine the best modification curves and modification ...
袁哲, 孙志礼, 郭瑜
doaj