Results 241 to 250 of about 497,791 (305)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

2-Hydroxyisobutyrylation and Phosphorylation Crosstalk Guides Metastasis Prediction and Immunotherapy in Esophageal Squamous Cell Carcinoma. [PDF]

MedComm (2020)
Li J, Li S, Yu X, Mu Q, Luo M, Wang Y, Liu Z, Gu C, Chen J, He W, Yang T, He Y, Pei X, Lin M, Li Z, Liu J, Zhao B, Zhang F, Liu J, Li B, Xu W.   +20 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Paclitaxel-eluting silicone airway stent with sustained drug release and potent anti-fibrotic activity. [PDF]

Front Bioeng Biotechnol
Ding M, Song J, Zhao C, Yang X, Ouyang Y, Zhuo Z, Chen X, Zhu R, Wang X, Yu T, Tian X, Yang F.   +11 more
europepmc   +1 more source

Novel Hertz Contact Intravascular Lithotripsy: Could We Achieve More in Balloon-Based Calcium Modification? [PDF]

J Clin Med
Mitsis A, Khattab E, Didagelos M, Theodoropoulos KC, Mavrogianni AD, Ziakas A, Fragakis N, Kassimis G.   +7 more
europepmc   +1 more source

Two Case Reports of Percutaneous Intravascular Lithotripsy for the Treatment of Severe Coronary Artery Calcification. [PDF]

Clin Case Rep
Guo LC, Hou CJ, Zeng YJ, Li W.
europepmc   +1 more source

Interferon in early MF: intersection of biology and evidence. [PDF]

Blood Adv
Mascarenhas J.
europepmc   +1 more source

Recent Advances on Extracellular Vesicles: A Natural Nanomaterial for Biomedical Application. [PDF]

Biomimetics (Basel)
Li F, Liu S, Xu S, Duan H, Wang Y, Li J.
europepmc   +1 more source