Results 101 to 110 of about 606,894 (280)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Experimental Study on Fluid Producing Profile Monitoring by Distributed Optical Fiber in Casing of Horizontal Wells

Shiyou jixie, 2023
The problem of water breakthrough in the production process of waterflooding horizontal wells in low permeability oilfield is increasingly outstanding,and water detection test is an important prerequisite for achieving efficient management of water ...
Li Dajian, Liu Guangsheng, Du Xiangqian, Yang Wenfei, Zhang Honggang   +4 more
doaj  

Phase-I monitoring of standard deviations in multistage linear profiles

Journal of Industrial Engineering International, 2017
In most modern manufacturing systems, products are often the output of some multistage processes. In these processes, the stages are dependent on each other, where the output quality of each stage depends also on the output quality of the previous stages.
Mahdiyeh Kalaei, Paria Soleimani, Seyed Taghi Akhavan Niaki, Karim Atashgar   +3 more
doaj   +1 more source

Antenna and base-station diversity for WSN livestock monitoring

, 2009
Antenna and base-station diversity have been applied to a wireless sensor network for the monitoring of live-stock.
Glover, Ian, Tachtatzis, Christos, Sasloglou, Konstantinos, ITI Scotland (Funder), Kwong, Kae Hsiang, Goh, Hock Guan, Michie, Craig, Andonovic, Ivan, Gilroy, Michael P., , ITI Scotland (Funder)   +9 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Distributed-Temperature-Sensing Using Optical Methods: A First Application in the Offshore Area of Campi Flegrei Caldera (Southern Italy) for Volcano Monitoring

Remote Sensing, 2016
A temperature profile 2400 m along the off-shore active caldera of Campi Flegrei (Gulf of Pozzuoli) was obtained by the installation of a permanent fiber-optic monitoring system within the framework of the Innovative Monitoring for Coastal and Marine ...
Stefano Carlino, Maurizio Mirabile, Claudia Troise, Marco Sacchi, Luigi Zeni, Aldo Minardo, Mauro Caccavale, Virág Darányi, Giuseppe De Natale   +8 more
doaj   +1 more source

EFFECTS OF ACOUSTIC STIMULATION ON BIOPHYSICAL PROFILE TESTING TIME [PDF]

Biophysical profile (BPP) test is the most commonly used antenatal test of fetal well-being. Purpose of this study is determining the influence of acoustic stimulation (AS) on BPP testing time.
رفاهی, سهیلا, جاوید مجد, مریم, مردی, افروز, پورعیسی, مسعود   +3 more
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Piecewise monitoring of nonlinear profiles using a multiple response linear model

, 2012
The air temperature often declines nonlinearly in the cool-down stage of a curing process. This nonlinear decline is correlated to the cosmetic quality of the high-pressure hose products. However, it is difficult to model nonlinear profiles for effective
Tsai, Tzong-Ru, Tsai, Tzong-Ru; Chang, Shing-I; Chou, Shih-Hsiung; Lin, Yu-Siang   +1 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source