Results 171 to 180 of about 3,277,020 (308)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Profiles (Summer/Fall, 2009) v.8 (2)

, 2009
In this issue Meeting the Need for Food Animal Veterinarians 3 VetFAST: Early Enrollment Program Benefits Graduates and Society 4 Annual Awards Ceremony Honors Students, Faculty, and Staff 6 Ph.D.
Stombaugh, Amanda: Cover design, Ames, Trevor: Dean, Graves, Brian: Communications and Marketing Manager, Howard, Fran: Writer, Staton, Sharon: Director of Advancement, Kirchoff, Sue: Editor, Writer & Designer   +5 more
core  

Robust enhanced leaf model implementation for beam-matched linear accelerators: Impact of physical leaf gap variations. [PDF]

J Appl Clin Med Phys
Lee S, Galavis PE, Jang S.
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Workers' Trust Funds and the Logic of Wage Profiles [PDF]

This paper defines a concept, a worker's trust fund, which is useful in analyzing optimal age-earnings profiles. The trust fund represents what a worker loses if dismissed from a job for shirking.
George A. Akerlof, Lawrence F. Katz
core  

Basic psychological need satisfaction profiles at work: person-centered links to job crafting and intrinsic motivation. [PDF]

Front Psychol
Coxen L.
europepmc   +1 more source

Profile [PDF]

Human Vaccines & Immunotherapeutics, 2013
openaire   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Generative artificial intelligence literacy profiles differ in academic self-efficacy and subjective well-being among adolescents. [PDF]

Front Psychol
Lee JY.
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source