Results 151 to 160 of about 3,277,020 (308)

Profiles of the Twin Cities Poor. Report Three. The Twin Cities Poor: A Housing Crisis

open access: yes, 1987
Where housing is located and how much it costs are problems for large numbers of low income households. One third of all low income households went without other basic necessities in 1984 to pay for housing, this third report in a series of six finds.The
Smith, Frederick W., Hagedorn, Dulcie
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

The Development of PROFILES teachers in Sweden

open access: yes, 2014
This presentation aims to share our experiences on the development of PROFILES with in-service science teachers for grade 7-9 in Sweden during the period of time from year 2012 to 2014. Inquiry-based science education (IBSE) has been addressed in science
Chang Rundgren, Shu-Nu,   +1 more
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Music identity profiles

open access: yes, 2017
First ShowingThe Music Identity Profile is a snapshot of influential listening experiences and musical encounters in time and space. The visual and sonic depiction of each music identity profile is unique.
Kaleva, D., van Hout, P.R., Elder, A.
core  

Beyond Traditional Glycemic Measures: CGM Glycemic Profiles Reveal Associations With Cardiometabolic Risk in Individuals Without Diabetes. [PDF]

open access: yesDiabetes Care
Bakhshi B   +16 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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