Results 121 to 130 of about 3,619,354 (396)

Stability of Resistance of Maize to Ear Rots (Fusarium graminearum, F. verticillioides and Aspergillus flavus) and Their Resistance to Toxin Contamination and Conclusions for Variety Registration

Toxins
All major ear rots (F. graminearum, F. verticillioides, and Aspergillus flavus) and their toxins are present in maize of preharvest origin in Hungary. Resistance can be an important tool in reducing the infection and toxin contamination from these rots ...
Akos Mesterhazy, Balazs Szabo, Denes Szieberth, Szabolcs Tóth, Zoltan Nagy, Tamas Meszlenyi, Beata Herczig, Attila Berenyi, Beata Tóth   +8 more
doaj   +1 more source

Governing for Genuine Profit [PDF]

Business corporations seek profit. That is, after subtracting cost, they maximize net revenue. Spillovers (both costs and benefits) involve trade-offs governing boards should make.
Michael J. O'Hara
core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Investment Size and Firm’s Value Under Profit Sharing Regulation [PDF]

In this article we analyse the effects of different regulatory schemes (price cap and profit sharing) on a firm’s investment of endogenous size. Using a real option approach in continuous time, we show that profit sharing does not affect a firm’s start ...
Carlo Scarpa, Michele Moretto, Paolo M. Panteghini   +2 more
core   +3 more sources

Do non-profits make a difference? Evaluating non-profit vis-à-vis for-profit organisations in social services [PDF]

This CPB Document provides a framework for the evaluation of non-profit organisations. This framework addresses the question under which conditions, and, if so, in what way non-profits should be stimulated. Essentially, in order to answer these questions,
Joëlle Noailly, Pierre Koning, Sabine Visser   +2 more
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Profit Sharing and Investment by Regulated Utilities: a Welfare Analysis [PDF]

We analyse the effects of different regulatory schemes (price cap and profit sharing) on a firm’s investment of endogenous size. Using a real option approach in continuous time, we show that profit sharing does not delay a firm’s start-up investment ...
Carlo Scarpa, Michele Moretto, Paolo M. Panteghini   +2 more
core  

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Cardio-Renal-Metabolic Syndrome in Patients with Chronic Kidney Disease: Relevance of the Problem; Pathogenetic Mechanisms; Diagnostics; Risk Factors; Prognosis; Research and Treatment Perspectives (Literature Review; Clinical Case Description)

Львівський клінічний вісник
Introduction. Cardiorenal metabolic syndrome (CRMS) is a complex, multisystem disorder resulting from the intricate interplay between cardiovascular, renal, and metabolic dysfunctions.
Kh. Abrahamovych, N. Chmyr, I. Dudar
doaj   +1 more source

Exclusionary Conduct, Effect on Consumers, and the Flawed Profit-Sacrifice Standard [PDF]

, 2006
The central thesis of this article is that the use of the profit-sacrifice test as the sole liability standard for exclusionary conduct, or as a required prong of a multi-pronged liability standard is fundamentally flawed.
Salop, Steven C.
core   +1 more source