Results 131 to 140 of about 931,689 (343)
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Are Profit and Profitability the Same Thing?
The terms “profit” and “profitability” are used quite frequently in everyday talk to mean the same thing. We often hear someone say “my business made a profit last year” or “my business was profitable.” But are the two statements equivalent? In this article, I’ll explain the two terms, outlining the difference between them, and discussing a few things ...
openaire +3 more sources
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
Respective Rights of Preferred and Common Stockholders in Surplus Profits
George Jarvis Thompson
openalex +2 more sources
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source
To profit or not to profit? That is the wrong question [PDF]
In social economy research, the issue of ‘profit’ (whether to make and/or distribute it) is a dominant framing concept. We argue that this dominance (even negatively referenced) maintains the hegemony of financial capital and the ‘for-profit’ paradigm. By refusing to accept a definition that labels organisations in terms of what they are not, scholars ...
Mcculloch, Maureen, Ridley-Duff, Rory
openaire +1 more source
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
Features of the relationship of adolescents’ self-esteem and their attitude to the teacher
The article discusses the problem of the relationship between self-esteem of adolescents and their attitude towards the school teacher. The self-esteem of adolescents is connected with the formation of their active cognitive activity, which serves as a ...
Olga N. Bakaeva+2 more
doaj +1 more source