Results 251 to 260 of about 3,821,770 (397)

A distributionally robust bilevel optimization model for wholesale-retail electricity market design. [PDF]

Sci Rep
Jia X, Ji P, Chen F, Deng H, Chen M, Zhuang X, Qi X, Tan Z.   +7 more
europepmc   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Evaluating medical education in Brazil: analysis of the National Student Performance Exam 2023. [PDF]

Front Med (Lausanne)
Rufino R, Neves MFT, Barbosa ADM, Povedano A, Schanaider A.   +4 more
europepmc   +1 more source

Profit, Directional Distance Functions, and Nerlovian Efficiency

, 1998
R. Chambers, Ya-Ting Chung, R. Färe
semanticscholar   +1 more source

Enriching NPK Mineral Fertilizer with Plant-Stimulating Peptides Increases Soilless Tomato Production, Grower Profit, and Environmental Sustainability

Michele Ciriello, Sara Rajabi Hamedani, Youssef Rouphael, Giuseppe Colla, Mariateresa Cardarelli   +4 more
openalex   +1 more source

Shifting-Profits Through Tax Loopholes. Evidence from Ecuador

, 2016
Cyril Chalendard
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

RESOUDRE UN PROBLEME D’ASYMETRIE D’INFORMATION EN S’ABSTENANT DE FAIRE DU PROFIT : LES ORGANISATIONS SANS BUT LUCRATIF REPONDENT-ELLES A UNE DEMANDE DE BIENS DE CONFIANCE

, 2011
Erwan Quéinnec
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Profit Shifting and Certainty on Allocation of Intangibles

, 2013
A. Musselli, Andrea Fusaro
openalex   +1 more source