Results 81 to 90 of about 3,228,375 (306)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Topological optimization of a ducted propeller of UAV
Авіаційно-космічна техніка та технологіяThe subject of this study is the minimization of the duct mass for a ducted propeller of UAV. The object of this study is a two-bladed ducted quadcopter propeller. The peripheral diameter of the propeller is 128 mm, and the hood is 2 mm thick.
Anton Balalaiev +4 more
doaj +1 more source
Strategic Outsourcing, Profit Sharing and Equilibrium Unemployment [PDF]
We analyze the following questions associated with outsourcing and profit sharing under imperfect labour markets. How does strategic outsourcing influence wage formation, profit sharing and employee effort when firms commit to optimal profit sharing ...
Koskela, Erkki, König, Jan
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Discrimination and Profit [PDF]
In this paper I analyze the relation between anti-discrimination policies applied by a company and its profit. Some authors argue that the problem of discrimination should not be approached at the company level, because this will negatively affect its ...
Dragos BIGU
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
ToxinsFusarium head blight is one of the greatest threats to global wheat production. Despite the special attention paid by researchers to resistance genetics, the stability of resistance and the expression of its epidemiological relationships have not been ...
Ákos Mesterhazy +4 more
doaj +1 more source
Common wisdom suggests that entry reduces profits of the incumbent firms. On the contrary, we show that if the incumbents differ in marginal costs and the entrants behave like Stackelberg followers, entry may benefit the incumbents who are relatively ...
Arijit Mukherjee, Laixun Zhao
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Inclusive governance in non-profit organisations [PDF]
, 2015 The study of private non-profit enterprises that offer general interest services is only at the start. The understanding of existing organisations resists an inclusive, public interest view of governance.
Borzaga, Carlo, Sacchetti, Silvia
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