Results 101 to 110 of about 142,507 (303)

Profit efficiency among maize farmers and implications for poverty alleviation and food security in Ghana

open access: yesScientific African, 2019
In this study, we analysed the profit efficiency of Ghanaian maize farmers using data collected from 576 farmers in four agro ecological zones of Ghana. The stochastic frontier translog profit function was the main method of analysis.
Camillus Abawiera Wongnaa   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Total factor productivity growth and technical change in a profit function framework

open access: yes, 2000
This paper develops a framework for measuring and decomposing TFP changes, within the parametric approach, by using directly the estimated parameters of a profit function.
Mergos, G.J., Karagiannis, G.
core  

A note on the endogeneity of the price of utility within the consumer’s static profit function

open access: yes
Utility function, Value function, Envelope theorem, Frischian profit function, Price of utility, D10, D60,
Robert Sproule
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Evolution of the objective/profit function P(Q(k)) for all simulation cases.

open access: yes, 2016
Evolution of the objective/profit function P(Q(k)) for all simulation cases.
Paris N. Stratis (3186873)   +4 more
core   +1 more source

A profit maximization model for sustainable inventory under preservation technology and linear time-dependent holding cost

open access: yesCroatian Operational Research Review
This paper presents sustainable inventory model with constant deterioration rate when holding cost is time dependent. Demand rate is price and stock dependent.
- Aashish, Pavan Kumar
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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