Results 161 to 170 of about 24,571 (203)

Transhumanism Without Transindividuation in the Age Without Epochality: Stiegler, Vice, and Radical Human Enhancement

Bioethics, EarlyView.
ABSTRACT At its core, transhumanism is utopic and apocalyptic: it tells us we will be saved through an imminent radical change of our being wrought by radical human enhancement (RHE) technologies. We are rushing, its supporters claim, towards a technological utopia so long as assorted techno‐phobes do not stand in the way.
Benjamin N. Parks
wiley   +1 more source

Rice sucrose transporter 1, <i>OsSUT1</i>, confers to alleviation of the high temperature stress in rice grain filling. [PDF]

Plant Biotechnol (Tokyo)
Kusano H, She KC, Matsubara K, Wang LL, Tsujiuchi K, Matsumoto R, Shiraishi M, Okubo Y, Yasui H, Sasaki T, Shimada H.   +10 more
europepmc   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

Advancing provitamin A biofortification in sorghum: from allele mining and marker development to prebreeding and breeding. [PDF]

Theor Appl Genet
Cruet-Burgos C, Banda L, Faye JM, Diatta C, Zapata D, Morris GP, Rhodes DH.   +6 more
europepmc   +1 more source

The lung is more than an organ of gas exchange: immunocompetency, platelets and implications for drug discovery

British Journal of Pharmacology, EarlyView.
Abstract The lungs have for a long time been recognised as having pharmacological significance as a specific organ to modulate the pharmacokinetics of endogenous substances needed to maintain homeostasis. The lungs are therefore the site of action of certain drugs that act on these homeostatic processes, resulting in systemic effects on the ...
Simon C. Pitchford
wiley   +1 more source

Genome-wide SSR marker development and application in molecular breeding of <i>Hemerocallis</i>. [PDF]

Front Plant Sci
Hou F, Guo X, Jia X, Hu M, Su J, Liang X, Qin Y, Gao Y, Xing G, Li S.   +9 more
europepmc   +1 more source

Evidence That the Protein Phosphatase Activity of PTEN Contributes to Embryonic Development and Tumor Suppression

Cancer Science, EarlyView.
Mice expressing only mutant PTEN Y138L, a protein which shows normal suppression of cellular AKT yet lacks protein phosphatase activity, die in utero, and heterozygous mice display a range of tumors. This indicates both the lipid and protein phosphatase activities of PTEN work together for normal tumor suppression and embryonic development.
Priyanka Tibarewal, Laura Spinelli, Nisha Kriplani, Helen Wise, Nadege Poncet, Giulia Marzano, Karen E. Anderson, Katarzyna M. Grzes, Zofia Varyova, Mahreen Adil, C. Peter Downes, Phillip T. Hawkins, Len R. Stephens, Kate G. Storey, Doreen A. Cantrell, Bart Vanhaesebroeck, Nicholas R. Leslie   +16 more
wiley   +1 more source

The RcMYB308-RcEGL1 module regulates cyanidin accumulation by targeting the RcF3'H promoter in pink roses. [PDF]

BMC Plant Biol
Sun W, Ji N, Yang J, Zhao S, Kuwantai A, Wang L, Wang L, Feng H.   +7 more
europepmc   +1 more source

The E‐cadherin‐Wnt‐mir‐994 Axis Repurposes a Cadherin Switch for Niche Robustness and Germline Stem Cell Maintenance

Cell Proliferation, EarlyView.
In the Drosophila ovarian niche, an E‐cadherin‐to‐N‐cadherin switch, mediated by Wnt‐mir‐994 signalling, is repurposed to ensure niche resilience. This compensatory mechanism maintains niche integrity and stem cell support upon E‐cadherin loss, revealing a robustness circuit.
Renjun Tu, Hiu Laam Yau, Runzhi Deng, Sarah E. Webb, Shiyuan Chen, Jianquan Ni, Ting Xie   +6 more
wiley   +1 more source

Analysis of Insect Resistance and Ploidy in Hybrid Progeny of Transgenic <i>BtCry1Ac</i> Triploid Poplar 741. [PDF]

Plants (Basel)
Zhou Y, Cai H, Zhao R, Wang C, Zhang J, Yang M, Wang J.   +6 more
europepmc   +1 more source