Results 181 to 190 of about 24,571 (203)

Compromised DNA replication in gut cells underlies sensitivity to genotoxic stress in the tardigrade Hypsibius exemplaris

The FEBS Journal, EarlyView.
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas, Pauline Fontanié, Benjamin Lacroix, Maria Dolores Molina, María Moriel‐Carretero   +4 more
wiley   +1 more source

Accurate detections of the heterozygous SNPs with rice genomic data and prediction of de novo spontaneous mutation rate. [PDF]

Plant Methods
Balimponya EG, Dwiyanti MS, Yamamori K, Sakaguchi S, Kanaoka Y, Koide Y, Kishima Y.   +6 more
europepmc   +1 more source

A guide to the ecological limitations of phage therapy of bacterial biofilms: Is what's best for the phage best for the physician?

The FEBS Journal, EarlyView.
Bacteriophages—viruses that kill bacteria—are promising weapons against bacterial biofilms: sessile communities notoriously resistant to antibiotics. Yet phages evolved not so much to eradicate bacteria as to obtain new bacteria to infect. That goal, however, may conflict with the physician's objective of complete bacterial clearance.
Stephen T. Abedon
wiley   +1 more source

Genome-wide association study revealed genomic regions associated with tuber quality traits in water yam (Dioscorea alata L.). [PDF]

PLoS One
Ouattara F, Agre PA, Adejumobi II, Olasanmi B, Stanley A, Sorho F, Dibi KEB, Akoroda MO, Bhattacharjee R.   +8 more
europepmc   +1 more source

The sorting nexin Snx21 promotes flotillin‐mediated endocytosis

The FEBS Journal, EarlyView.
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs, Enikő Lakatos, Dalma Feil‐Börcsök, Gábor Juhász, Regina Mező, Asha Kiran Maddali, András Blastyák, Aladár Pettkó‐Szandtner, Hajnalka Laczkó‐Dobos, Gábor Juhász   +9 more
wiley   +1 more source

Dicer is essential for proper maturation, composition, and function in the postnatal retina. [PDF]

iScience
Kang S, Larbi D, Bruns E, Hahne K, Khodadadi-Jamayran A, Sreenivasaiah C, Carneiro ML, Andrade M, Batsuuri K, Chen S, Jager J, Viswanathan S, Clark BS, Wohl SG.   +13 more
europepmc   +1 more source

Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle

The FEBS Journal, EarlyView.
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini, Konstantinos Poalas, Margaux Versapuech, Clarisse Berlioz‐Torrent, Katy Janvier   +4 more
wiley   +1 more source

Characterization of a New Powdery Mildew Resistance Gene on Chromosome 1R from Hexaploid Triticale Transferred to Wheat. [PDF]

Plants (Basel)
Luo Y, Jiang C, Li L, Jiang T, Tan JYT, Boro A, Yang E, Li G, Yang Z.   +8 more
europepmc   +1 more source

A lipid‐sensitive food choice behavior influences aging outcomes from a longevity‐promoting diet

The FEBS Journal, EarlyView.
C. elegans are exposed to a variety of bacteria in their natural environment and must be able to distinguish between beneficial and detrimental food sources. We show that C. elegans exposed to the bacterium from their natural habitat, Methylobacterium, disrupts lipid homeostasis, causing worms to avoid this bacterial species and choose the laboratory ...
Nicole L. Stuhr, Carmen M. Ramos, Chris D. Turner, Alexander A. Soukas, Sean P. Curran   +4 more
wiley   +1 more source

Autophagy-regulated mitochondrial inheritance controls early CD8⁺ T cell fate commitment. [PDF]

Nat Cell Biol
Borsa M, Lechuga-Vieco AV, Kayvanjoo AH, Jenkins E, Yazicioglu Y, Compeer EB, Richter FC, Rapp S, Mitchell R, Youdale T, Bui H, Kuuluvainen E, Dustin ML, Sinclair LV, Katajisto P, Simon AK.   +15 more
europepmc   +1 more source