Results 121 to 130 of about 24,050 (247)

Climate-Resilient F₃ Progenies of <i>Coffea arabica</i>: Agronomic Traits and Antibiosis to <i>Hypothenemus hampei</i>. [PDF]

Plants (Basel)
Molina D, Flórez-Ramos CP, Montoya EC, Medina R, Benavides P.   +4 more
europepmc   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

A Novel Acetylcholine Nanosensor for Single Vesicle Storage and Sub‐Quantal Exocytosis in Living Neurons and Organoids

Angewandte Chemie, EarlyView.
Schematic representation of M@E@CF nanosensors for detecting vesicular storage and release in cholinergic neurons and brain organoids. (A) Nano‐tip microelectrodes modification via molds fabricated through 3D printing. (B) the reaction mechanism for acetylcholine detection at the electrode interface.
Wanying Zhu, Yufan Zhang, Hanwen Yu, Da Wang, Xinyue Zhang, Xiaowen Du, Shanshan Wu, Bingzhi Li, Yizhou Zhang, Hongliang Xin, Xing Guo, Yan Liu   +11 more
wiley   +2 more sources

Genetic Gains and Field Validation of Synthetic Populations in Tropical Maize Using Selection Indexes and REML/BLUP. [PDF]

Plants (Basel)
Sousa AMCB, Resende MPM, Crispim-Filho AJ, Miranda GV, Reis EFD.   +4 more
europepmc   +1 more source

Optimization and verification of high‐fat diet formulation for establishing a rat model of obesity‐related precocious puberty

Animal Models and Experimental Medicine, EarlyView.
We identified 45% HFD as the optimal formulation to establish a juvenile rat model of obesity‐related precocious puberty. It elicits robust phenotypic (early vaginal opening, obesity), histological (advanced ovarian development), and endocrine (elevated HPG axis hormones) alterations, with leptin‐mediated GnRH secretion as a core mechanistic driver ...
Jiayi Gong, Wei Qian, Deji Song, Kang Li, Li Zhang, Li Shi   +5 more
wiley   +1 more source

Non-Destructive Estimation of Leaf Size and Shape Characteristics in Advanced Progenies of <i>Coffea arabica</i> L. from Intraspecific and Interspecific Crossing. [PDF]

Plants (Basel)
Unigarro CA, Darghan AE, Cayón Salinas DG, Flórez-Ramos CP.   +3 more
europepmc   +1 more source

Gorab deficiency in skin dermis accelerates aging and is associated with dysregulation of RCHY1‐mediated P53 ubiquitination

Animal Models and Experimental Medicine, EarlyView.
Based on a dermis fibroblast Gorab knockout mouse model, this study revealed that Gorab deficiency promotes skin aging by influencing RCHY1, causing a decrease in P53 ubiquitination, damaging the activity of HDAC2, further resulting in the accumulation of aging‐related proteins (P53, P21, P16) and a reduction in extracellular matrix (ECM) components ...
Yanhong Li, Wei Liang, Yanfeng Xu, Yunlin Han, Wenjie Zhao, Siyuan Wang, Wei Deng, Chuan Qin   +7 more
wiley   +1 more source

Gap junction-mediated signaling coordinates Rhodopsin coupling for Drosophila color vision. [PDF]

Biol Open
Zhang X, Shinjo R, Kitamata M, Otsune S, Nakagoshi H.   +4 more
europepmc   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Rapid recovery of homozygous <i>Pr</i> gene introgression lines in Indian tropical cauliflower backgrounds through combined use of morphological and molecular markers. [PDF]

Front Plant Sci
Singh S, Kumar S, Verma V.
europepmc   +1 more source