Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Immune checkpoint blockade (ICB) has transformed the treatment of mismatch repair‐deficient (dMMR) colorectal cancer but produces no meaningful benefit in advanced mismatch repair‐proficient (pMMR) disease. In the neoadjuvant setting, however, pathological responses have been reported in a subset of pMMR tumors, suggesting that clinical ...
Kimihiro Yamashita +4 more
wiley +1 more source
Continued overexpression of <i>EPSPS</i> transgene enhances fitness in multigeneration crop-wild rice hybrids and its long-term environmental impact. [PDF]
Front Plant SciJiang XQ +7 more
europepmc +1 more source
Explaining the Origin of Negative Poisson's Ratio in Amorphous Networks With Machine Learning
Advanced Intelligent Discovery, EarlyView.This review summarizes how machine learning (ML) breaks the “vicious cycle” in designing auxetic amorphous networks. By transitioning from traditional “black‐box” optimization to an interpretable “AI‐Physics” closed‐loop paradigm, ML is shown to not only discover highly optimized structures—such as all‐convex polygon networks—but also unveil hidden ...
Shengyu Lu, Xiangying Shen
wiley +1 more source
Multitrait Evaluation of Drought Tolerance at the Seedling Stage in Advanced Backcross Germplasm Derived from Sugarcane × <i>Tripidium arundinaceum</i>. [PDF]
Plants (Basel)Liu J +9 more
europepmc +1 more source
American Journal of Agricultural Economics, EarlyView.Abstract While multiple factors explain low adoption rates of improved varieties by small‐scale farmers in sub‐Saharan Africa, a key supply‐side constraint is the limited availability of seed embodying new traits in the volume, quality, price, and timeliness required by farmers. This constraint is partly attributable to classical failures in the market
Dawit Mekonnen +5 more
wiley +1 more source
Combining ability and gene action for flowering, plant height, grain size, and yield in rice (<i>Oryza sativa L</i>.) genotypes. [PDF]
Front Plant SciJeke E +4 more
europepmc +1 more source
American Journal of Botany, EarlyView.Abstract Premise Changing climates are leading to more frequent and severe heat waves, potentially threatening plant populations. Both acclimation to stress and selection for heat‐escape or heat‐resistance phenotypes occur during heat waves. However, plastic responses and selection do not necessarily interact cohesively—even producing trait responses ...
Lana F. Gaspard +4 more
wiley +1 more source
Broadening the genetic horizon of rice: comparative insights from gamma radiation and EMS-induced mutagenesis. [PDF]
BMC Plant BiolRashid M +7 more
europepmc +1 more source
American Journal of Community Psychology, EarlyView.Abstract Firefighters face an array of stressors due to the demands of their occupation, leading to a high prevalence of mental health challenges. Social prescribing represents a novel approach to healthcare that emphasizes a holistic view of health and wellbeing.
Janice Ikeda +2 more
wiley +1 more source
Screening olour mango half-sib progenies for dwarfing, vigour, and climate resilience. [PDF]
Sci RepShukoor A +8 more
europepmc +1 more source