Results 121 to 130 of about 440,683 (312)

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

open access: yesAdvanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu   +18 more
wiley   +1 more source

Superparasitism and its effects on the fitness of the larval parasitoid, Coccygidium luteum (Hymenoptera: Braconidae)

open access: yesEuropean Journal of Entomology
The tendency of parasitoid wasps to oviposit in a previously parasitised host (superparasitism) has long been considered detrimental to their fitness, until recent evidence showed that it may be an adaptive strategy.
Patrick BESEH   +3 more
doaj   +1 more source

The system of genetic exchange in Trypanosoma brucei and other trypanosomatids [PDF]

open access: yes, 2007
In this chapter, we discuss our current understanding of the systems of genetic exchange in trypanosomatids and the im-pact the recent genome projects have had on this area of research.
MacLeod, A., Tait, A., Turner, C.M.R.
core  

Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor

open access: yesAdvanced Science, EarlyView.
Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang   +4 more
wiley   +1 more source

Feeding preferences and progeny production of Rhyzopertha dominica (Fabricius 1792) (Coleoptera: Bostrichidae) in small grains

open access: yesBiologica Nyssana, 2018
The lesser grain borer, Rhyzopertha dominica (Fabricius, 1792) (Coleoptera: Bostrichidae) is a primary pest of stored wheat. Many authors studied its development on this cereal.
Vladimir Perišić   +6 more
doaj   +1 more source

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

open access: yesAdvanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui   +9 more
wiley   +1 more source

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

open access: yesAdvanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza   +19 more
wiley   +1 more source

Individual multivariate REML/BLUP in the presence of genotype x environment interaction in rubber tree (Hevea) breeding

open access: yesCrop Breeding and Applied Biotechnology, 2002
The present study was carried out to estimate genetic parameters and additive genetic values by the individual REML/BLUP procedure for rubber tree [Hevea brasiliensis (Willd. ex Adr.
Reginaldo Brito da Costa   +3 more
doaj  

Efficacy of the Combination of λ-Cyhalothrin and Chlorantraniliprole Against Four Key Storage Pests

open access: yesInsects
With over 1000 species of pests causing losses in both the quantity and quality of stored food, insect contamination poses significant challenges. The present study assesses the efficacy of the combination of λ-cyhalothrin and chlorantraniliprole against
Waqas Wakil   +5 more
doaj   +1 more source

Rappaccini's Progeny [PDF]

open access: yesJournal of the Royal Society of Medicine, 2002
openaire   +2 more sources

Home - About - Disclaimer - Privacy