Results 41 to 50 of about 234,306 (316)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Probability of Causation for Lung Cancer After Exposure to Radon Progeny: A Comparison of Models and Data [PDF]
, 1994 The estimates of lung cancer risk due to the exposure to radon decay products are based on different data sets from underground mining and on different mathematical models that are used to fit the data.
Kunz, E. +5 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Insects, 2018 Most stored-grain pest insects increase their population within a relatively short time, causing serious damage to stored products. Sitophilus oryzae (L.) is one of the world’s major stored-grain pest insects and was chosen as the model insect for ...
Guillermo Pablo López-García +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2016 Genotypes of each Tibouchina pulchra progeny plant. We germinated seeds from adult individuals and sampled from ten to 21 progeny individuals when the seedlings reached a size enough to perform DNA extraction.
Sazima, Marlies +11 more
core +1 more source
Relationships among Charolais sire expected progeny differences and actual progeny performance in commercial herds [PDF]
, 2003 Data on Charolais-sired calves were analyzed to evaluate progeny performance related to sire expected progeny differences (EPD) in a large data set of commercial crossbred cattle in several herds across the United States. The traits analyzed were birth
R.E. Williams +5 more
core +1 more source
, 2023 Progeny born per sire at 2a) Ranch B and 2b) Ranch D. Each number on the x-axis represents a ram while the y-axis show the total number of progeny a ram sired. Blue indicates male lambs & pink indicates female lambs.
Morgan P. Doran (16872158) +9 more
core +1 more source