Results 41 to 50 of about 270,399 (239)

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

DACH1 suppresses breast cancer as a negative regulator of CD44. [PDF]

open access: yes, 2017
Dachshund homolog 1 (DACH1), a key cell fate determination factor, contributes to tumorigenesis, invasion, metastasis of human breast neoplasm. However, the exact molecular mechanisms for the anti-tumor roles of DACH1 in breast carcinoma are still lack ...
Kuang, Dong   +6 more
core   +2 more sources

Parent‐to‐Child Information Disclosure in Pediatric Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor   +12 more
wiley   +1 more source

Transcription factor ZEB1 coordinating with NuRD complex to promote oncogenesis through glycolysis in colorectal cancer

open access: yesFrontiers in Pharmacology
BackgroundColorectal cancer (CRC) is an aggressive primary intestinal malignancy with the third-highest incidence and second-highest mortality among all cancer types worldwide.
Tianyang Gao   +12 more
doaj   +1 more source

ING4 (inhibitor of growth family, member 4) [PDF]

open access: yes, 2011
Review on ING4 (inhibitor of growth family, member 4), with data on DNA, on the protein encoded, and where the gene is ...
Greco, A, Miranda, C
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Machine Learning and Artificial Intelligence for Infectious Disease Surveillance, Diagnosis, and Prognosis

open access: yesViruses
Advances in high-throughput technologies, digital phenotyping, and increased accessibility of publicly available datasets offer opportunities for big data to be applied in infectious disease surveillance, diagnosis, treatment, and outcome prediction ...
Brandon C. J. Cheah   +2 more
doaj   +1 more source

An integrative analysis of cancer gene expression studies using Bayesian latent factor modeling

open access: yes, 2010
We present an applied study in cancer genomics for integrating data and inferences from laboratory experiments on cancer cell lines with observational data obtained from human breast cancer studies.
Chen, Julia Ling-Yu   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Risk factors in gastric cancer [PDF]

open access: yes, 2010
STATE OF THE ART: Gastric cancer (GC) is still a major health problem worldwide due to its frequency, poor prognosis and limited treatment options. At present prevention is likely to be the most effective means of reducing the incidence and mortality ...
COMPARE, DEBORA   +2 more
core  

Home - About - Disclaimer - Privacy