Results 61 to 70 of about 507,437 (241)
Complexes of trees and nested set complexes [PDF]
We exhibit an identity of abstract simplicial complexes between the well-studied complex of trees and the reduced minimal nested set complex of the partition lattice. We conclude that the order complex of the partition lattice can be obtained from the complex of trees by a sequence of stellar subdivisions.
arxiv
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
A Generalization Method of Partitioned Activation Function for Complex Number [PDF]
A method to convert real number partitioned activation function into complex number one is provided. The method has 4em variations; 1 has potential to get holomorphic activation, 2 has potential to conserve complex angle, and the last 1 guarantees interaction between real and imaginary parts.
arxiv
The influence of feature selection methods on accuracy, stability and interpretability of molecular signatures [PDF]
Motivation: Biomarker discovery from high-dimensional data is a crucial problem with enormous applications in biology and medicine. It is also extremely challenging from a statistical viewpoint, but surprisingly few studies have investigated the relative
A Ivshina+36 more
core +5 more sources
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
An Empirical Investigation of Correlation between Code Complexity and Bugs [PDF]
There have been many studies conducted on predicting bugs. These studies show that code complexity, such as cyclomatic complexity, correlates with the presence of bugs in code. In this paper, we intend to find the correlation between path complexity and bugs.
arxiv
Prognosis-search complex for mesothermal gold deposits. P. 3. Petrochemical and geochemical criteria
The relevance of the work is defined by the necessity to develop after hundred year investigations hydrothermal gold deposits formation theory instead of the four competing ones - granitogene, basaltogene, metamorphogene, polygene retaining in ore geology.
openaire +2 more sources
Risk factors in gastric cancer [PDF]
STATE OF THE ART: Gastric cancer (GC) is still a major health problem worldwide due to its frequency, poor prognosis and limited treatment options. At present prevention is likely to be the most effective means of reducing the incidence and mortality ...
COMPARE, DEBORA+2 more
core
MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors [PDF]
MRE11 is a component of the MRE11/RAD50/NBS1 (MRN) complex, whose activity is essential to control faithful DNA replication and to prevent accumulation of deleterious DNA double-strand breaks.
Bartolazzi, Armando+19 more
core +3 more sources
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source