Results 101 to 110 of about 3,490,181 (385)

Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis.

Gastroenterology, 2017
Primary liver cancer is the second leading cause of cancer-related death worldwide and therefore a major public health challenge. We review hypotheses of the cell of origin of liver tumorigenesis and clarify the classes of liver cancer based on molecular
D. Sia, A. Villanueva, S. Friedman, J. Llovet   +3 more
semanticscholar   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Identification of Topological Features in Renal Tumor Microenvironment Associated with Patient Survival [PDF]

, 2017
Motivation As a highly heterogeneous disease, the progression of tumor is not only achieved by unlimited growth of the tumor cells, but also supported, stimulated, and nurtured by the microenvironment around it.
Cheng, Jun, Feng, Qianjin, Huang, Kun, Mo, Xiaokui, Parwani, Anil, Wang, Xusheng   +5 more
core   +1 more source

BCLC strategy for prognosis prediction and treatment recommendation Barcelona Clinic Liver Cancer (BCLC) staging system. The 2022 update.

Journal of Hepatology, 2021
M. Reig, A. Forner, J. Rimola, J. Ferrer-Fábrega, M. Burrel, Á. García-Criado, R. Kelley, P. Galle, V. Mazzaferro, R. Salem, B. Sangro, A. Singal, A. Vogel, J. Fuster, C. Ayuso, J. Bruix   +15 more
semanticscholar   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Impact Monitoring for Aircraft Smart Composite Skins Based on a Lightweight Sensor Network and Characteristic Digital Sequences

Sensors, 2018
Due to the growing use of composite materials in aircraft structures, Aircraft Smart Composite Skins (ASCSs) which have the capability of impact monitoring for large-scale composite structures need to be developed.
Lei Qiu, Xiaolei Deng, Shenfang Yuan, YongAn Huang, Yuanqiang Ren   +4 more
doaj   +1 more source

Clinical prediction models to inform individualized decision-making in subfertile couples : a stratified medicine approach [PDF]

, 2014
Funding This work was supported by a Chief Scientist Office Postdoctoral Training Fellowship in Health Services Research and Health of the Public Research (Ref PDF/12/06).
Bhattacharya, S., McLernon, D.J., Mol, B.W.J., Steyerberg, E.W., te Velde, E.R.   +4 more
core   +3 more sources

Significance of HbA1c Test in Diagnosis and Prognosis of Diabetic Patients

Biomarker Insights, 2016
Diabetes is a global endemic with rapidly increasing prevalence in both developing and developed countries. The American Diabetes Association has recommended glycated hemoglobin (HbA1c) as a possible substitute to fasting blood glucose for diagnosis of ...
Shariq I. Sherwani, H. Khan, Aishah A. Ekhzaimy, A. Masood, M. Sakharkar   +4 more
semanticscholar   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Early Jurassic A-type granite and monzodiorite from the Baoji batholith: Implication for tectonic transition from post-collision to post-orogenic extension in the Qinling Orogenic Belt, China

Frontiers in Earth Science
Introduction: The early Jurassic granitoids in the Qinling Orogenic Belt (QOB) play a crucial role in understanding the tectonic implications for the geological evolution of China.
Xiangkuan Gong, Nijiati Abuduxun, Xiaoliang Jia, Yuanfeng Cheng, Hongming Cai, Xueqian Wu, Haodong Yang   +6 more
doaj   +1 more source