Renal Failure, 2018 Introduction: As glomerular filtration rate (GFR) decreases, serum phosphate level increases. Previous reports indicated that serum phosphate level was associated with mortality in patients on dialysis.
Akiko Owaki +10 more
doaj +1 more source
PROGNOSIS OF MONTHLY UNEMPLOYMENT RATE IN THE EUROPEAN UNION THROUGH METHODS BASED ON ECONOMETRIC MODELS [PDF]
In this paper we propose the prognosis of the unemployment rate in the European Union through the Box-Jenkins method and the TRAMO/SEATS method as well as the detection of the method which proves to provide the best results. The monthly unemployment rate
Balan Christiana Brigitte +1 more
core
A nomogram to predict prognosis after surgery for young patients with hepatocellular carcinoma [PDF]
, 2020 Xingchen Li +8 more
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting the noise: improving biomarkers with ensembles of data analysis methodologies. [PDF]
, 2012 BackgroundThe advent of personalized medicine requires robust, reproducible biomarkers that indicate which treatment will maximize therapeutic benefit while minimizing side effects and costs.
Boutros, Paul C +8 more
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
DETERMINANTS OF ENERGY CONSUMPTION & FUEL BASE SAFETY [PDF]
, 2018 On the base of studying the current situation in the world mining and fuel consumption author make the prognosis of the country’s economic development and involving new conception of mine ...
KICKI, Jerzy
core
Case-based reasoning combined with statistics for diagnostics and prognosis [PDF]
, 2012 Many approaches used for diagnostics today are based on a precise model. This excludes diagnostics of many complex types of machinery that cannot be modelled and simulated easily or without great effort.
Funk, Peter, Olsson, Tomas
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Integrative analysis of the colorectal cancer proteome : potential clinical impact [PDF]
, 2016 Peer ...
Alnabulsi, Abdo, Murray, Graeme I.
core +2 more sources