Results 101 to 110 of about 1,897,175 (319)

Role of Liquid Biopsy for Early Detection, Prognosis, and Therapeutic Monitoring of Hepatocellular Carcinoma [PDF]

open access: yes
The global prevalence of hepatocellular carcinoma (HCC) is getting worse, leading to an urgent need for improved diagnostic and prognostic strategies.
Faris Alrumaihi
core   +1 more source

The prognosis of epilepsy

open access: yesSeizure, 2001
The cardinal question for a person developing seizures is 'What is the likelihood that they will go away?' 'Prognosis' refers to the possible outcomes of a disease and the frequency at which they can be expected to occur. Prognostic factors may include demographic features, disease-specific indicators (e.g.
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Grobner Bases for Nonlinear DAE Systems of Analog Circuits [PDF]

open access: yesComputer Science Journal of Moldova, 2008
Systems of differential equations play an important role in modelling and analysis of many complex systems e.g. in electronics and mechanics. The following article is concerned with a symbolic analysis approach for reduction of the differential index of ...
Silke J. Spang
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Enhanced Fatigue Crack Detection in Complex Structure with Large Cutout Using Nonlinear Lamb Wave

open access: yesSensors
The large cutout structure is a key component in the bottom skin of an airplane wing, and is susceptible to developing fatigue cracks under service loads.
Suofeng Zhang, Yuan Liu, Shenfang Yuan
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A zero-dimensional approach to compute real radicals [PDF]

open access: yesComputer Science Journal of Moldova, 2008
The notion of real radicals is a fundamental tool in Real Algebraic Geometry. It takes the role of the radical ideal in Complex Algebraic Geometry. In this article I shall describe the zero-dimensional approach and efficiency improvement I have found ...
Silke J. Spang
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Comparative Study on Pore Characteristics and Methane Adsorption Capacity of the Lower Silurian Longmaxi Shales with Different Lithofacies

open access: yesFractal and Fractional
In this study, shale samples with diverse lithofacies from the Lower Silurian Longmaxi Formation in the Fuling Field were investigated to evaluate the variations in pore characteristics and methane adsorption capacity (MAC) of different shale lithofacies.
Xiaoming Zhang   +9 more
doaj   +1 more source

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