THE NON-RELATIONSHIP OF ACTIVE CELLULAR DIVISION TO THE PROGNOSIS IN MALIGNANT DISEASE. [PDF]
Guthrie McConnell
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The prognosis for prognosis remains excellent [PDF]
openaire +3 more sources
Handwriting analysis for diagnosis and prognosis of Parkinson’s disease [PDF]
At present, there are no quantitative, objective methods for diagnosing the Parkinson disease. Existing methods of quantitative analysis by myograms suffer by inaccuracy and patient strain; electronic tablet analysis is limited to the visible drawing ...
Brause, Rüdiger W.+2 more
core
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
An Address ON RECENT ADVANCES IN THE DIAGNOSIS, PROGNOSIS, AND TREATMENT OF HEART DISEASE: THE POLYGRAPH: Given at the Opening Meeting of the Session of the Toronto Academy of Medicine [PDF]
Frank W. Price
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Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Background Percutaneous coronary intervention (PCI) of the left main coronary artery (LMCA) for stable angina has steadily increased. Outcomes stratified by sex are inconclusive and limited.
Warkaa Shamkhani+6 more
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The Bradshaw Lecture ON PROGNOSIS IN RELATION TO TREATMENT OF TUBERCULOSIS OF THE GENITOURINARY ORGANS: Delivered before the Royal College of Surgeons of England [PDF]
RickmanJ. Godlee
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Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
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