Results 211 to 220 of about 2,795,577 (349)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Correlation analysis of clinical efficacy and prognosis of endoscopic submucosal dissection of early gastric cancer with peripheral blood indexes. [PDF]

Front Oncol
Ying X, Huang Y, Zhang L, Hu J, Zhao B.
europepmc   +1 more source

Prognosis of Crohn's disease.

, 1981
J F Mayberry
openalex   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

CXCL12-mediated T cell infiltration drives breast cancer metastasis. [PDF]

Clin Exp Med
Liu X, Chen C, Liu L, Tang J, Zhang H, Jin G, Chen Y.   +6 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Distribution of gut microbiota and prognostic value in elderly patients with coronary atherosclerosis: a preliminary culture-based study. [PDF]

BMC Cardiovasc Disord
Du H, Xu X, Lei Q, Qian C, Wang Z, Yu X, Lei Q.   +6 more
europepmc   +1 more source

The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics

, 2020
Kaitlyn H. Smith, Amit Budhraja, J.A. Lynch, Kathryn G. Roberts, John C. Panetta, Jon P. Connelly, Meghan E. Turnis, Shondra M. Pruett‐Miller, John D. Schuetz, Charles G. Mullighan, Joseph T. Opferman   +10 more
openalex   +2 more sources

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

The correlation of umbilical cord blood quality and placental function with neonatal outcomes in fetal growth restriction. [PDF]

Front Med (Lausanne)
Zou L, Zeng Y, Zhao L, Shi C, Yang C, Zhu Y.   +5 more
europepmc   +1 more source