Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay +15 more
wiley +1 more source
Frailty and nutritional status as prognostic factors in older adults with heart failure: a public health perspective. [PDF]
Li J, Liu M, Wang J.
europepmc +1 more source
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin +8 more
wiley +1 more source
Integrative Analysis of Steroid Metabolism-Based Molecular Subtypes Reveals Prognostic Subtypes and Therapeutic Implications in Gastric Cancer. [PDF]
Li L, Zhu H, Gao G, Chen H.
europepmc +1 more source
National Trends in Types of Hospice Disenrollment Among Older Adults With Dementia, 2012-2019. [PDF]
Hunt LJ +7 more
europepmc +1 more source
Downregulation of miR203 Induces Overexpression of <i>PIK3CA</i> and Predicts Poor Prognosis of Gastric Cancer Patients [Retraction]. [PDF]
europepmc +1 more source
Building an interpretable machine learning prognosis prediction model-based on baseline examinations of patients with esophageal cancer undergoing surgery. [PDF]
Zhan R, Wang Q.
europepmc +1 more source
Risk Factors for Poor Neurological Outcomes at Discharge in Tuberculous Meningitis: Disease Severity, Host Factors, and Drug Therapy. [PDF]
Yu Y +9 more
europepmc +1 more source

