Primary Signet-Ring Carcinoma (Linitus Plastica) of the Colorectum presenting as Subacute Intestinal Obstruction [PDF]
, 2012 Primary Signet-ring cell carcinoma (Linitus Plastica) of the colon and rectum is a rare form of adenocarcinoma of the large intestine and has been reported to have an extremely poor prognosis. We report a case of Primary Signet-ring cell carcinoma of the
Jagtap, SS +4 more
core
High MYC mRNA expression is more clinically relevant than MYC DNA amplification in triple-negative breast cancer [PDF]
, 2019 DNA abnormalities are used in inclusion criteria of clinical trials for treatments with specific targeted molecules. MYC is one of the most powerful oncogenes and is known to be associated with triple-negative breast cancer (TNBC).
Dasgupta, Subhamoy +6 more
core +2 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Estimated pulse wave velocity (ePWV), a marker of arterial stiffness, is strongly associated with cardiovascular events and all‐cause death in the general population.
Mustafa Al‐jarshawi +6 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Clinical prediction models to inform individualized decision-making in subfertile couples : a stratified medicine approach [PDF]
, 2014 Funding This work was supported by a Chief Scientist Office Postdoctoral Training Fellowship in Health Services Research and Health of the Public Research (Ref PDF/12/06).
Bhattacharya, S. +4 more
core +3 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
EoL: Towards Quality Care at the End of Life [PDF]
, 2009 Palliative and end-of-life care must be available to all who require it, regardless of location, age, income, diagnosis or prognosis, and social and cultural background.
core
A principal stratification approach to assess the differences in prognosis between cancers caused by hormone replacement therapy and by other factors [PDF]
, 2010 Several recent studies have reported that women who have used hormone replacement therapy (HRT), and developed breast cancer, tend to have a better prognosis than women with breast cancer who have not used HRT.
Humphreys, Keith +2 more
core +1 more source
Renal Failure, 2018 Introduction: As glomerular filtration rate (GFR) decreases, serum phosphate level increases. Previous reports indicated that serum phosphate level was associated with mortality in patients on dialysis.
Akiko Owaki +10 more
doaj +1 more source
Superior prognosis stratification for stage III colon cancer using log odds of positive lymph nodes (LODDS) compared to TNM stage classification: the Japanese study group for postoperative follow-up of colorectal cancer [PDF]
, 2020 Shimpei Ogawa +4 more
openalex +1 more source