Results 171 to 180 of about 1,782,739 (310)

Combined elevation of pre-treatment γ-glutamyltransferase and lactate dehydrogenase as independent prognosticator for metastatic renal cell carcinoma undergoing immune-based therapy. [PDF]

Sci Rep
Uhlig A, Mattigk A, Sondermann M, Hoeh B, Cano Garcia C, Klümper N, Cox A, Hahn O, Schmucker P, Flegar L, Vollemaere J, Zengerling F, Banek S, Ellinger J, Huber J, Zeuschner P, Kalogirou C, Erdmann K, German Society of Residents in Urology (GeSRU) Academics Renal Cell Carcinoma Work Group.   +18 more
europepmc   +1 more source

Epidermal growth factor receptor expression analysis in chemotherapy-naive patients with advanced non-small-cell lung cancer treated with gefitinib or placebo in combination with platinum-based chemotherapy [PDF]

, 2008
Abderrahim Fandi, AP Meert, AS Merseburger, D Veale, DA Eberhard, David H. Johnson, DC Spaulding, DJ Slamon, DS Salomon, DW Bell, F Cappuzzo, F Cappuzzo, FA Shepherd, FR Hirsch, G Giaccone, Giuseppe Giaccone, International Conference on Harmonisation, J Brabender, J Gawrychowski, JG Paez, JP Kallio, JR Woodburn, Judith S. Ochs, L Bingle, M Volm, M-S Tsao, Mette Janas, N Thatcher, R Sordella, Renee B. Iacona, RI Nicholson, Roy S. Herbst, RS Herbst, RS Herbst, SJ Pocock, TJ Lynch, U Gatzemeier, Y Nakayama, Y Ohsaki   +38 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Role of cone-beam computed tomography in predicting root canal treatment success: A systematic review and meta-analysis. [PDF]

Saudi Dent J
Alqahtani S.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Prognostic analysis and development of a prognostic model for EML4-ALK-positive lung cancer patients treated with ALK-TKIs. [PDF]

Front Med (Lausanne)
Liu R, Su C, Su H, Wang L.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Letter to the Editor: Regarding Electrocardiographic Predictors of Major Adverse Cardiovascular Events in Women With INOCA. [PDF]

Ann Noninvasive Electrocardiol
Kaya OK.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Prognostic Value of HALP Score in Rheumatic Mitral Stenosis: A Long-Term Follow-Up Study. [PDF]

Clin Cardiol
Butt SA.
europepmc   +1 more source