BackgroundColon adenocarcinoma (COAD) is a common digestive system malignancy with high mortality and poor prognosis. Accumulating evidence indicates that choline metabolism is closely related to tumorigenesis and development.
Cong Liu +27 more
doaj +1 more source
EarlyR: A Robust Gene Expression Signature for Predicting Outcomes of Estrogen Receptor–Positive Breast Cancer [PDF]
Introduction Early stage estrogen receptor (ER)-positive breast cancer may be treated with chemotherapy in addition to hormone therapy. Currently available molecular signatures assess the risk of recurrence and the benefit of chemotherapy; however ...
Badve, Sunil S. +2 more
core +1 more source
Tamoxifen resistance-related ceRNA network for breast cancer
Background: Tamoxifen (TMX) is one of the most widely used drugs to treat breast cancer (BC). However, acquired drug resistance is still a major obstacle to its application, rendering it crucial to explore the mechanisms of TMX resistance in BC.
Zipeng Qiao +11 more
doaj +1 more source
Prognostic indicators of early and late death in children admitted to district hospital in Kenya: cohort study [PDF]
OBJECTIVES: To identify clinical indicators of immediate, early, and late mortality in children at admission to a sub-Saharan district hospital and to develop prognostic scores. DESIGN: Prospective cohort study.
Berkley, JA +8 more
core +1 more source
A Novel Six-Gene Signature for Prognosis Prediction in Ovarian Cancer
Ovarian cancer (OC) is the most malignant tumor in the female reproductive tract. Although abundant molecular biomarkers have been identified, a robust and accurate gene expression signature is still essential to assist oncologists in evaluating the ...
Xin Pan, Xiaoxin Ma
doaj +1 more source
Communicating prognostic uncertainty in potential end-of-life contexts: experiences of family members [PDF]
Background: This article reports on the concept of “communicating prognostic uncertainty” which emerged from a mixed methods survey asking family members to rank their satisfaction in seven domains of hospital end-of-life care. Methods: Open-ended
Gallagher, Romayne, Krawczyk, Marian
core +2 more sources
Identifying and selecting optimal prognostic health indicators in the context of predictive maintenance is essential to obtain a good model and make accurate predictions.
Valentin Hamaide , François Glineur
doaj +1 more source
Stochastic RUL calculation enhanced with TDNN-based IGBT failure modeling [PDF]
Power electronics are widely used in the transport and energy sectors. Hence, the reliability of these power electronic components is critical to reducing the maintenance cost of these assets.
Alghassi, Alireza +2 more
core +1 more source
Prognosis and prognostic research: validating a prognostic model
Prognostic models are of little clinical value unless they are shown to work in other samples.
Altman, D +3 more
openaire +4 more sources
Evidence based cardiology - Psychosocial factors in the aetiology and prognosis of coronary heart disease: systematic review of prospective cohort studies [PDF]
Summary points: In healthy populations, prospective cohort studies show a possible aetiological role for type A/hostility (6/14 studies), depression and anxiety (11/11 studies), psychosocial work characteristics (6/10 studies), social support (5/8 ...
Hemingway, H., Marmot, M.
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