Results 91 to 100 of about 866,858 (352)

Incremental value of radiomics with machine learning to the existing prognostic models for predicting outcome in renal cell carcinoma [PDF]

, 2023
Jiajun Xing, Yiyang Liu, Zhongyuan Wang, Aiming Xu, Shifeng Su, Sipeng Shen, Zengjun Wang, Zengjun Wang, Zengjun Wang   +8 more
openalex   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Integrating single-cell regulatory atlas and multi-omics data for differential treatment response and multimodal predictive modeling in CDK 4/6 inhibitor-treated breast cancer

Frontiers in Oncology
IntroductionCDK4/6 inhibitors are cornerstone therapies for advanced HR+/HER2- breast cancer, yet treatment response heterogeneity remains a major clinical challenge. This study integrates single-cell regulatory landscapes with multi-omics data to decode
Li Yan, Li Yan, Sijie Chen, Sijie Chen, Ran Ran, Ran Ran, Shidi Zhao, Shidi Zhao, Jing Huang, Jing Huang, Jin Yang, Jin Yang, Jin Yang, Jin Yang   +13 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Transcriptomic profile assessment for preeclampsia prediction and early diagnostics

Акушерство, гинекология и репродукция
Aim: to develop a model for predicting preeclampsia (PE) based on the clinically most significant differentially expressed plasma microRNAs.Materials and Methods. A prospective observational comparative study was conducted with 62 women, divided into two
A. V. Melnik, V. E. Solovyova, Yu. O. Yatsenko, A. E. Filippova, E. G. Asryan, T. Е. Seitumerov, E. R. Myshak, Yu. A. Chernysheva, S. A. Ziyadinova, V. O. Kononenko, M. R. Kadyrova, A. A. Denisenko, K. T. Ismagilova, D. V. Mushinsky, L. E. Sorokina   +14 more
doaj   +1 more source

Outcomes following oesophagectomy in patients with oesophageal cancer: a secondary analysis of the ICNARC Case Mix Programme Database [PDF]

, 2009
Introduction: This report describes the case mix and outcomes of patients with oesophageal cancer admitted to adult critical care units following elective oesophageal surgery in England, Wales and Northern Ireland.
Alderson, Derek, Cromwell, David A., Harrison, D. A. (David A.), Palser, Thomas R., Park, Daniel P., Perkins, Gavin D., Rowan, Katherine M., Smith, F. Gao (Fang Gao), Welch, Catherine A.   +8 more
core   +4 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Inflammation-nutrition biomarker model for survival prediction in lung cancer patients with concurrent tuberculosis

Frontiers in Molecular Biosciences
ObjectivesTo explore the prognostic value of eight inflammation-nutrition biomarkers in patients with lung cancer and tuberculosis as no multidimensional prognostic models for this comorbid population are available currently.MethodologyA retrospective ...
Hongqi Zhou, Zihao Zhao, Jinhai Wang, Weiyun Jin, Bensong Xian, Lindi Li, XiangWen Nie, WeiWei Wu, Ran Chen, QiZhen Xie, HaiXia Wu, WeiWei Jiang, Min Tang, YuXin Li   +13 more
doaj   +1 more source

Prognostic models for predicting recurrence and survival in women with endometrial cancer [PDF]

, 2021
Y. Louise Wan, Iman El Sayed, Thomas D. J. Walker, Bryn Russell, Ellena Badrick, Alexandra McAleenan, Richard J. Edmondson, Emma J. Crosbie   +7 more
openalex   +1 more source

Implementation of a novel online condition monitoring thermal prognostic indicator system

, 2014
This research aims to develop a reliable and robust online condition monitoring thermal prognostic indicator system which will reduce the risk of failures in a Power System Network.
Christou, S., Lewin, P.L., Pilgrim, J.A., Swingler, S.G.   +3 more
core