Results 71 to 80 of about 14,715,516 (253)

Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures [PDF]

, 2011
Background: Current prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers.
Pusztai, Lajos, Lajos Pusztai, Schmidt Marcus, Karn, Thomas, Lars Hanker, Holtrich Uwe, Ruckhäberle Eugen, Volkmar Müller, Liedtke, Cornelia, Karn Thomas, Shiang Christine Y., Rody Achim, Gätje, Regine, Solbach Christine, Eugen Ruckhäberle, Pusztai Lajos, Müller, Volkmar, Cornelia Liedtke, Rody, Achim, Ahr Andre, Ruckhäberle, Eugen, Marcus Schmidt, Christine Y Shiang, Solbach, Christine, Gaetje Regine, Ahr, André, Andre Ahr, Thomas Karn, Hanker Lars, Achim Rody, Schmidt, Marcus, Shiang, Christine Y., Hanker, Lars, Takayuki Iwamoto, Holtrich, Uwe, Iwamoto Takayuki, Manfred Kaufmann, Liedtke Cornelia, Uwe Holtrich, Christine Solbach, Müller Volkmar, Iwamoto, Takayuki, Kaufmann Manfred, Kaufmann, Manfred, Regine Gaetje   +44 more
core   +1 more source

Programmed cell death-related prognostic genes mediate dysregulation of the immune microenvironment in triple-negative breast cancer

Frontiers in Immunology
BackgroundProgrammed Cell death (PCD) encompasses a spectrum of genetically regulated cell death processes and plays a double-edged sword role in neoplastic progression and therapeutic resistance of Triple-Negative Breast Cancer(TNBC)through the tumor ...
Xiaowen Ma, Hui Shan, Zhao Chen, Rongzi Shao, Ning Han   +4 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Hypoxia-associated genes as predictors of outcomes in gastric cancer: a genomic approach

Frontiers in Immunology
ObjectiveTo investigate the effects of hypoxia-related genes in stomach adenocarcinoma (STAD) and construct an excellent prognostic model.MethodsRNA expression data and clinical details were retrieved from the TCGA and GEO database dataset.
Shuo Yang, Shuo Yang, Yuhao Jiang, Zhonghua Yang, Zhonghua Yang   +4 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Identification of DAP3 as candidate prognosis marker and potential therapeutic target for hepatocellular carcinoma

Frontiers in Immunology
BackgroundAmong malignant tumors, hepatocellular carcinoma (HCC) is both prevalent and highly lethal. Most patients with advanced-stage liver cancer have a poor prognosis.
Liu-Xia Yuan, Zhi-Qiang Yue, Qin-Rong Ma, Peng Zhang, Feng Xiao, Lin Chen   +5 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

A Novel Prognostic Model Based on Prognostic Nutritional Index and Systemic Immune-Inflammation Index for Cancer Patients Treated with Immune Checkpoint Inhibitors

Cancer Management and Research
Jingxian Mao,1,* Huaijuan Guo,1,* Jingjing Yang,1,* Jiaxin Wang,1 Mingyang Tao,1 Ying Wang,1 Xuebing Yan,1 Min Li21Department of Oncology, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, People’s ...
Mao J, Guo H, Yang J, Wang J, Tao M, Wang Y, Yan X, Li M   +7 more
doaj  

Development of a prognostic model for hepatocellular carcinoma based on microvascular invasion characteristic genes by spatial transcriptomics sequencing

Frontiers in Immunology
Microvascular invasion (MVI) is an independent risk factor for the recurrence and metastasis of hepatocellular carcinoma (HCC), associated with poor prognosis.
Xiaolan Mu, Lili Pan, Xicheng Wang, Changcheng Liu, Changcheng Liu, Yu Li, Yongchao Cai, Yongchao Cai, Zhiying He, Zhiying He, Zhiying He   +10 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source