Results 91 to 100 of about 863,398 (307)

Inflammation-nutrition biomarker model for survival prediction in lung cancer patients with concurrent tuberculosis

Frontiers in Molecular Biosciences
ObjectivesTo explore the prognostic value of eight inflammation-nutrition biomarkers in patients with lung cancer and tuberculosis as no multidimensional prognostic models for this comorbid population are available currently.MethodologyA retrospective ...
Hongqi Zhou, Zihao Zhao, Jinhai Wang, Weiyun Jin, Bensong Xian, Lindi Li, XiangWen Nie, WeiWei Wu, Ran Chen, QiZhen Xie, HaiXia Wu, WeiWei Jiang, Min Tang, YuXin Li   +13 more
doaj   +1 more source

Economic Growth in Georgia: Historical Perspectives and Prognosis [PDF]

While output declined in virtually all transition economies in the initial years, the speed and extent of the recovery that followed has varied widely across these countries. The paper examines some aspects of transition experiences of 1990s and dynamics
Alexander Milnikov, Irakli Rodonaia, Tatiana Papiashvili   +2 more
core   +1 more source

Prognostic robustness of serum creatinine based AKI definitions in patients with sepsis: a prospective cohort study [PDF]

, 2015
Background: It is unclear how modifications in the way to calculate serum creatinine (sCr) increase and in the cut-off value applied, influences the prognostic value of Acute Kidney Injury (AKI).
Dhondt, Annemieke, Lameire, Norbert, Van Biesen, Wim, Vanholder, Raymond, Vanmassenhove, Jill   +4 more
core   +2 more sources

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

The suppressive role of GLS in radiosensitivity and irradiation-induced immune response in LUAD: integrating bioinformatics and experimental insights

Frontiers in Immunology
BackgroundRadiotherapy elicits immune activation, thereby synergistically enhancing systemic tumor control when combined with immunotherapy. Glutaminase (GLS), a key enzyme for glutamine metabolism, has been found to regulate glutamine availability ...
Peicheng Jiang, Zhifeng Jiang, Su Li, Su Li, Ye-Xiong Li, Yuqiong Chen, Xinyan Li   +6 more
doaj   +1 more source

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

The Impact of Tertiary Lymphoid Structures on Tumor Prognosis and the Immune Microenvironment in Colorectal Cancer

Biomedicines
Background: Colorectal cancer (CRC) ranks as the third most common cancer worldwide. Tertiary lymphoid structures (TLSs), organized immune cell aggregates in non-lymphoid tissues, are linked to chronic inflammation and tumorigenesis. However, the precise
Leyi Zhao, Lingze Xi, Yani Liu, Guoliang Wang, Mingtong Zong, Peng Xue, Shijie Zhu   +6 more
doaj   +1 more source

Development of a composite model derived from cardiopulmonary exercise tests to predict mortality risk in patients with mild-to-moderate heart failure [PDF]

, 2014
Objective: Cardiopulmonary exercise testing (CPET) is used to predict outcome in patients with mild-to-moderate heart failure (HF). Single CPET-derived variables are often used, but we wanted to see if a composite score achieved better predictive power ...
Carroll, Sean, Clark, Andrew L, Cleland, John G, Goode, Kevin M, Ingle, Lee, Rigby, Alan S, Sloan, Rebecca   +6 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Programmed cell death-related prognostic genes mediate dysregulation of the immune microenvironment in triple-negative breast cancer

Frontiers in Immunology
BackgroundProgrammed Cell death (PCD) encompasses a spectrum of genetically regulated cell death processes and plays a double-edged sword role in neoplastic progression and therapeutic resistance of Triple-Negative Breast Cancer(TNBC)through the tumor ...
Xiaowen Ma, Hui Shan, Zhao Chen, Rongzi Shao, Ning Han   +4 more
doaj   +1 more source