Results 61 to 70 of about 561,995 (314)

Prognosis of cholangiocarcinoma patients based on multiple patterns of programmed cell death, integrated analysis of the immune microenvironment and drug sensitivity

Frontiers in Genetics
BackgroundCholangiocarcinoma (CHOL) is a highly malignant bile duct cancer with a poor prognosis and rising incidence. Programmed cell death (PCD) plays a crucial role in cancer biology, influencing tumor immunity and treatment response.
Yupeng Xu, Yupeng Xu, Jian Sun, Xin Yan, Zhenliao Mao, Yiming Chen   +5 more
doaj   +1 more source

Development of a 3 RNA Binding Protein Signature for Predicting Prognosis and Treatment Response for Glioblastoma Multiforme

Frontiers in Genetics, 2021
Purpose: Glioblastoma multiforme (GBM) is the most widely occurring brain malignancy. It is modulated by a variety of genes, and patients with GBM have a low survival ratio and an unsatisfactory treatment effect.
Ruohan Sun, Yujun Pan, Long Mu, Yaguang Ma, Hong Shen, Yu Long   +5 more
doaj   +1 more source

Statistical considerations on prognostic models for glioma [PDF]

Neuro-Oncology, 2015
Given the lack of beneficial treatments in glioma, there is a need for prognostic models for therapeutic decision making and life planning. Recently several studies defining subtypes of glioma have been published. Here, we review the statistical considerations of how to build and validate prognostic models, explain the models presented in the current ...
Molinaro, Annette M, Wrensch, Margaret R, Jenkins, Robert B, Eckel-Passow, Jeanette E   +3 more
openaire   +4 more sources

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

External validation of the Oncotype DX breast cancer recurrence score nomogram and development and validation of a novel machine learning-based model to predict postoperative overall survival and guide adjuvant chemotherapy in ER positive, Her-2 negative breast cancer patients: a retrospective cohort study

Frontiers in Oncology
BackgroundThis study aims to externally validate the performance of the Oncotype DX (ODX) breast cancer (BC) recurrence score nomogram in predicting adjuvant chemotherapy (ACT) for BC after surgery and subsequently develop a machine learning-based model ...
Dongdong Wang, Xinfeng Wang, Xin Yang
doaj   +1 more source

Clustering analysis and prognostic model based on PI3K/AKT-related genes in pancreatic cancer

Frontiers in Oncology, 2023
BackgroundPancreatic cancer is one of most aggressive malignancies with a dismal prognosis. Activation of PI3K/AKT signaling is instrumental in pancreatic cancer tumorigenesis.
Xiangying Deng, Xiangying Deng, Xu He, Xu He, Xu He, Zehua Yang, Jing Huang, Lin Zhao, Min Wen, Min Wen, Xiyuan Hu, Zizheng Zou, Zizheng Zou, Zizheng Zou   +13 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Derivation and Validation of a Prognostic Model for Acute Decompensated Cirrhosis Patients

, 2023
Yue Zhang,* Peng Chen,* Wang Zhang, Chenkai Huang,* Xuan Zhu* Department of Gastroenterology, Jiangxi Province and Jiangxi Clinical Research Center for Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang ...
Zhang W, Huang C, Chen P, Zhang Y, Zhu X
core  

Comparison of tumour-based (Petersen Index) and inflammation-based (Glasgow Prognostic Score) scoring systems in patients undergoing curative resection for colon cancer [PDF]

, 2009
After resection, it is important to identify colon cancer patients, who are at a high risk of recurrence and who may benefit from adjuvant treatment. The Petersen Index (PI), a prognostic model based on pathological criteria is validated in Dukes' B and ...
Foulis, A.K., R F McKee, McMillan, D.C., A K Foulis, Maxwell, F., McKee, R.F., C S D Roxburgh, F Maxwell, Crozier, J.E.M., Roxburgh, C.S.D., Anderson, J.H., J H Anderson, D C McMillan, P G Horgan, J E M Crozier, Horgan, P.G., Brown, J., J Brown   +17 more
core   +1 more source

Construction and validation of a prognostic model based on cuproptosis-related genes in patients with multiple myeloma

陆军军医大学学报
Objective‍　‍To explore the potential cuproptosis-related genes (CRGs) in patients with multiple myeloma (MM) and develop a prognostic model for improving prognosis and revealing features of the MM immune microenvironment.
KANG Zhongmin, KANG Zhongmin, LI Licheng
doaj   +1 more source