Results 41 to 50 of about 863,398 (307)

In silico identification and verification of Tanshinone IIA-related prognostic genes in hepatocellular carcinoma

Frontiers in Immunology
BackgroundCurrently, adequate treatment and prognostic prediction means for Hepatocellular Carcinoma (HCC) haven’t entered into medical vision. Tanshinone IIA (TanIIA) is a natural product, which can be utilized as a potential treatment of HCC due to its
Lichao Qian, Zhongchi Xu, Tianjiong Luo, Zhao Gao, Kun Cheng, Xiaolong He, Zhongai Zhang, Shuai Ren, Yinxing Zhu   +8 more
doaj   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Prognostic value assessment and in vitro validation of mitochondria-ferroptosis-related genes in multiple myeloma

Scientific Reports
Multiple myeloma (MM) is a malignant plasma cell tumor. Mitochondria-related genes (MRGs) are significant inducers of ferroptosis. However, research on the involvement of mitochondria-ferroptosis-related genes (MFRGs) in the MM is relatively scarce, and ...
Jing Wu, Chen Li, Jiayou Zhang, Jing Su, Yuting Xiao, Linhua Ji   +5 more
doaj   +1 more source

Identification and validation of mRNA profiles linked to ATP- induced cell death represent a novel prognostic model for breast cancer

Frontiers in Immunology
BackgroundCell death mechanisms are integral to the pathogenesis of breast cancer (BC), with ATP-induced cell death (AICD) attracting increasing attention due to its distinctive specificity and potential therapeutic applications.MethodsThis study ...
Zhongwen Zhang, Haolong Zhang, Zheng Zhang, Doblin Sandai, Ping Lu, Haoling Zhang, Haoling Zhang, Haoling Zhang, Jianjun Wu   +8 more
doaj   +1 more source

Weight gain at 3 months of antiretroviral therapy is strongly associated with survival: evidence from two developing countries [PDF]

, 2009
BACKGROUND: In developing countries, access to laboratory tests remains limited, and the use of simple tools such as weight to monitor HIV-infected patients treated with antiretroviral therapy should be evaluated.
Arnaud Fontanet, Bagchi, Bisson, Bonard, Bonnet, Calmy, Christine Genevier, Diggle, Elisabeth Szumilin, Erikstrup, Etard, Ferradini, Ferradini, Gilks, Harries, Ivers, Jerene, Laurent Ferradini, Madec, Malvy, Mar Pujades, Paton, Saghayam, San Lio, Severe, Shetty, Shikuma, Silva, Spacek, Stringer, Suna Balkan, Tang, Van Damme, Yoann Madec   +33 more
core   +3 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Comparison of the prognostic value of tumour and patient related factors in patients undergoing potentially curative surgery for colon cancer [PDF]

, 2009
<b>Aim</b>: To comprehensively compare the prognostic value of tumour and patient-related factors in patients undergoing curative surgery for colon cancer.
Benson, Brown, Compton, Cooper, Crozier, Dukes, Forrest, Gabay, Gasser, Halazun, Hauser, Ishizuka, Kacevska, Kandemir, Kim, Kobayashi, Lee, Leitch, Lindmark, Maltoni, McMillan, McMillan, Mehrkhani, Michael, Moertel, Monreal, Morris, Petrelli, Ramsey, Roxburgh, Sasaki, Sharma, Smith, Taylor, Thynne, Vakkila, Vibert, Viganó, Walsh, Wanebo, Wang, Wolpin   +41 more
core   +1 more source

Analysis of the predictive postoperative recurrence performance of three lymph node staging systems in patients with colon cancer

Frontiers in Oncology
BackgroundColon cancer remains a major cause of cancer-related deaths worldwide, with recurrence post-surgery, posing a significant challenge. Accurate lymph node (LN) staging is critical for prognosis and treatment decisions, but traditional systems ...
Ning Meng, Zhiqiang Wang, Yaqi Peng, Xiaoyan Wang, Wenju Yue, Le Wang, Wenqian Ma   +6 more
doaj   +1 more source

Validation of a Melanoma Prognostic Model [PDF]

Archives of Dermatology, 1998
A "clinically accessible," 4-variable (patient age, patient sex, tumor location, and tumour thickness) prognostic model has been published previously. This model evaluated variables that were commonly available to the clinician. Because models are heuristic, validity of a prognostic model should be evaluated in a population different from the original ...
D J, Margolis, A C, Halpern, T, Rebbeck, L, Schuchter, R L, Barnhill, J, Fine, M, Berwick   +6 more
openaire   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source