Results 31 to 40 of about 561,995 (314)

A glycolysis-related gene signatures in diffuse large B-Cell lymphoma predicts prognosis and tumor immune microenvironment

Frontiers in Cell and Developmental Biology, 2023
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma which that highly aggressive and heterogeneous. Glycolysis has been implicated in the regulation of tumor microenvironment (TME) and development.
Yingying Cui, Yingying Cui, Changsen Leng, Changsen Leng, Changsen Leng   +4 more
doaj   +1 more source

The age-adjusted international prognostic index 2 (A-FLIPI2) for elderly patients with follicular lymphoma

Heliyon
Follicular lymphoma (FL) is a common B-cell lymphoma and typically affects the elderly population. It is urgently required to enhance our comprehension of disease-specific outcomes in elderly FL patients and identify a reliable predictive indicator to ...
Jiesong Wang, Junlei Jia, Jingwei Yu, Jing Liu, Meng Gao, Hengqi Liu, Lanfang Li, Lihua Qiu, Shiyong Zhou, Bin Meng, Wenchen Gong, Zhengzi Qian, Xianhuo Wang, Huilai Zhang   +13 more
doaj   +1 more source

Progression of disease within 24 months (POD24) in multiple myeloma implicates poor prognosis and limitations of current prediction models for POD24

Scientific Reports
Multiple myeloma (MM) is a common hematological malignancy, and its prognostic factors have been extensively studied. Progression of disease within 24 months (POD24) suggests a poor prognosis in many malignancies, but is rarely mentioned in MM.
Yongqin Cao, Yingying Gong, Qingqing Wang, Jun Xia, Xin Zhou, Chao Sun   +5 more
doaj   +1 more source

Distinct clinico-genomic factors drive outcomes in patients with myelofibrosis and disease-related anemia

Frontiers in Hematology
BackgroundDisease related anemia in myelofibrosis (MF) is common and prognostically detrimental. Anemia in MF poses a therapeutic challenge as it contributes to poor quality of life and often interferes with JAK inhibitor therapy.
Somedeb Ball, Najla H. Al Ali, Akriti G. Jain, Luis E. Aguirre, Seongseok Yun, Onyee Chan, Zhuoer Xie, David A. Sallman, Jeffrey Lancet, Eric Padron, Rami S. Komrokji, Andrew T. Kuykendall   +11 more
doaj   +1 more source

Establish immune-related gene prognostic index for esophageal cancer

Frontiers in Genetics, 2022
Background: Esophageal cancer is a tumor type with high invasiveness and low prognosis. As immunotherapy has been shown to improve the prognosis of esophageal cancer patients, we were interested in the establishment of an immune-associated gene ...
Caiyu Guo, Caiyu Guo, Fanye Zeng, Hui Liu, Jianlin Wang, Xue Huang, Judong Luo   +6 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Prognostic Modelling with Dynamic Bayesian Networks [PDF]

, 2009
In this paper, we review the application of dynamic Bayesian networks to prognostic modelling. An example is provided for illustration. With this example, we show how the equipment’s reliability decays over time in the situation where repair is not ...
McNaught, Ken R., Zagorecki, A.
core  

Construction of a solid Cox model for AML patients based on multiomics bioinformatic analysis

Frontiers in Oncology, 2022
Acute myeloid leukemia (AML) is a highly heterogeneous hematological malignancy. The bone marrow (BM) microenvironment in AML plays an important role in leukemogenesis, drug resistance and leukemia relapse.
Fu Li, Jiao Cai, Jiao Cai, Jia Liu, Shi-cang Yu, Xi Zhang, Yi Su, Lei Gao   +7 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

In silico identification and verification of Tanshinone IIA-related prognostic genes in hepatocellular carcinoma

Frontiers in Immunology
BackgroundCurrently, adequate treatment and prognostic prediction means for Hepatocellular Carcinoma (HCC) haven’t entered into medical vision. Tanshinone IIA (TanIIA) is a natural product, which can be utilized as a potential treatment of HCC due to its
Lichao Qian, Zhongchi Xu, Tianjiong Luo, Zhao Gao, Kun Cheng, Xiaolong He, Zhongai Zhang, Shuai Ren, Yinxing Zhu   +8 more
doaj   +1 more source