Results 161 to 170 of about 866,858 (352)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Immunoinfiltration Analysis of Mitochondrial Damage‐Related Genes in Lung Adenocarcinoma and Construction of a Classification and Prognostic Model Integrated With WGCNA and Machine Learning Algorithms

Cancer Medicine
Background Lung adenocarcinoma (LUAD) exhibits molecular heterogeneity, with mitochondrial damage affecting progression. The relationship between mitochondrial damage and immune infiltration, and Weighted Gene Co‐expression Network Analysis (WGCNA ...
Jirong Zhang, Lin Lin
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Physicians’ Attitudes Regarding the Use of Prognostic Models in End-of-life Care (316-B) [PDF]

, 2012
Paul K. J. Han, Norbert Hootsmans, Sarah Hallen   +2 more
openalex   +1 more source

Improving HCC Prognostic Models after Liver Resection by AI-Extracted Tissue Fiber Framework Analytics [PDF]

, 2023
Rokas Stulpinas, Mindaugas Morkūnas, Allan G. Rasmusson, Julius Drachneris, Renaldas Augulis, Aistė Gulla, Kęstutis Strupas, Arvydas Laurinavičius   +7 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Integrated Multi-Omics Analysis Unveils Distinct Molecular Subtypes and a Robust Immune–Metabolic Prognostic Model in Clear Cell Renal Cell Carcinoma [PDF]

Yan Zhu, Shihui Yu, Dan Yang, Yu Tian, Yi Liu, Wenlong Du   +5 more
openalex   +1 more source

B-004 * PROGNOSTIC MODEL OF SURVIVAL FOR TYPICAL BRONCHIAL CARCINOID TUMOURS: ANALYSIS OF 1090 PATIENTS ON BEHALF OF THE ESTS NEUROENDOCRINE TUMOURS WORKING GROUP [PDF]

, 2014
Pier Luigi Filosso, Francesco Guerrera, Andrea Evangelista, Stefan Welter, Paloma Moreno-Moreno, Erino Angelo Rendina, W. D. Travis, Paul S. Thomas, I. Sarkaria   +8 more
openalex   +1 more source

Supplementary Dataset from Novel Mouse Models of Bladder Cancer Identify a Prognostic Signature Associated with Risk of Disease Progression

, 2023
Soonbum Park, Lijie Rong, Tomasz B. Owczarek, Matteo Di Bernardo, Rivka L. Shoulson, Chee Wai Chua, Jaime Y. Kim, Amir Lankarani, Prithi Chakrapani, Talal Syed, James M. McKiernan, David B. Solit, Michael M. Shen, Hikmat Al‐Ahmadie, Cory Abate‐Shen   +14 more
openalex   +1 more source

ATIC inhibits autophagy in hepatocellular cancer through the AKT/FOXO3 pathway and serves as a prognostic signature for modeling patient survival [PDF]

, 2021
Hao Zhang, Peng Xia, Jie Liu, Zhang Chen, Weijie Ma, Yufeng Yuan   +5 more
openalex   +1 more source