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Four-gene Prognostic Signature and Risk of Brain Metastasis of Lung Adenocarcinoma. [PDF]

open access: yesMol Carcinog
Gong Z   +11 more
europepmc   +1 more source

Integrated machine learning analysis of 30 cell death patterns identifies a novel prognostic signature in glioma. [PDF]

open access: yesFront Cell Dev Biol
Huang M   +11 more
europepmc   +1 more source
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Prognostic immunologic signatures in epithelial ovarian cancer

Oncogene, 2022
Epithelial Ovarian Cancer (EOC) is a deadly gynecologic malignancy in which patients frequently develop recurrent disease following initial platinum-taxane chemotherapy. Analogous to many other cancer subtypes, EOC clinical trials have centered upon immunotherapeutic approaches, most notably programmed cell death 1 (PD-1) inhibitors.
Nicole E. James   +2 more
openaire   +2 more sources

Diagnostic and Prognostic Sarcoma Signatures

Molecular Diagnosis & Therapy, 2008
Sarcomas are a diverse group of childhood and adult tumors that arise from mesenchymal tissue. In contrast to epithelial tumors, most of which are defined by a specific organ system, sarcomas can arise virtually anywhere in the body, such that their characteristic histopathology and clinical presentation form the core diagnostic criteria.Precise ...
Elai, Davicioni   +2 more
openaire   +2 more sources

Autophagy‐related prognostic signature for breast cancer

Molecular Carcinogenesis, 2015
Autophagy is a process that degrades intracellular constituents, such as long‐lived or damaged proteins and organelles, to buffer metabolic stress under starvation conditions. Deregulation of autophagy is involved in the progression of cancer. However, the predictive value of autophagy for breast cancer prognosis remains unclear.
Yunyan, Gu   +10 more
openaire   +2 more sources

Prognostic and Predictive Signatures for Treatment Decisions

Biomarkers in Medicine, 2018
We develop a subgroup selection procedure using both prognostic and predictive biomarkers to identify four patient subpopulations: low- and high-risk responders, and low- and high-risk nonresponders.We utilize three regression models to identify three sets of biomarkers: S, prognostic biomarkers; T, predictive biomarkers; and U, prognostic and ...
Un Jung, Lee   +3 more
openaire   +2 more sources

Taking Prognostic Signatures to the Clinic

2020
In this chapter, the authors focus on genomic predictors related to prognosis and the way these predictors are expected to impact patient management in the future and accelerate the transition from the “empirical” to “tailored” oncology. Clinicians have long recognized that the diagnosis of breast cancer includes tumor types with different natural ...
Ignatiadis, Michail, Sotiriou, Christos
openaire   +2 more sources

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