Results 331 to 340 of about 1,264,892 (364)

Prognostic Signature and Discrimination Signature of Lung Adenocarcinoma based on Pyroptosis-Related Genes

Combinatorial Chemistry & High Throughput Screening, 2023
Background: The clinical value of pyroptosis-related genes (PRGs) in lung adenocarcinoma (LUAD) remains obscure. Objective: The study attempts to explore PRGs in LUAD, which will enable an understanding of LUAD from the perspective of PRGs. Method: Lung adenocarcinoma patients were diagnosed using pathology, and their clinical information was ...
Guo-Sheng, Li, Hui-Ping, Lu, Li, Gao, Jian-Di, Li, Rong-Quan, He, Hua-Fu, Zhou, Shang-Wei, Chen, Jun, Liu, Zong-Wang, Fu, Jin-Liang, Kong, Jiang-Hui, Zeng, Juan, He, Gang, Chen   +12 more
openaire   +2 more sources

Understanding Prognostic Gene Expression Signatures in Lung Cancer

Clinical Lung Cancer, 2009
In non-small-cell lung cancer (NSCLC), molecular profiling of tumors has led to the identification of gene expression patterns that are associated with specific phenotypes and prognosis. Such correlations could identify early-stage patients who are at increased risk of disease recurrence and death after complete surgical resection and who might benefit
Chang-Qi, Zhu, Melania, Pintilie, Thomas, John, Dan, Strumpf, Frances A, Shepherd, Sandy D, Der, Igor, Jurisica, Ming-Sound, Tsao   +7 more
openaire   +2 more sources

Nine-Gene Prognostic Signature for Myelodysplastic Syndrome

American Journal of Clinical Pathology, 2023
Abstract Introduction/Objective Myelodysplastic Syndrome (MDS) is a family of clonal hematopoietic malignancies found frequently in the seventh and eight decades, supporting that aging and acquired somatic mutations drive development of the disease. Without a cure, the prognosis is poor.
K Lyapichev, L Kazacheuskaya, M D Memon, M Ong, J Cotelingam, K Beedupalli, L Centeno, A Patil   +7 more
openaire   +1 more source

Prognostic Applications of Gene Expression Signatures in Breast Cancer

Oncology, 2009
Analysis by DNA microarrays has led to the identification of molecular subtypes of breast carcinomas that show a distinct expression profile. Several studies have demonstrated that this ‘intrinsic subtype’ classification has a strong prognostic value.
Normanno N., De Luca A., Carotenuto P., Lamura L., Oliva I., D'Alessio A.   +5 more
openaire   +3 more sources

An individualized immune prognostic signature in nasopharyngeal carcinoma

Oral Oncology
Immune-related characteristics can serve as reliable prognostic biomarkers in various cancers. Herein, we aimed to construct an individualized immune prognostic signature in nasopharyngeal carcinoma (NPC).This study retrospectively included 455 NPC samples and 39 normal healthy nasopharyngeal tissue specimens. Samples from Gene Expression Omnibus (GEO)
Guanjie Qin, Xiaofei Liao, Bin Zhang, Yixin Su, Huiyun Yang, Yuan Xie, Rongjun Zhang, Xiangyun Kong, Shufang Liao, Cancan Chen, Yunyan Mo, Jinxuan Dai, Huaying Tang, Yuting duan, Wei Jiang   +14 more
openaire   +2 more sources

MicroRNA prognostic signature in malignant pleural mesothelioma.

Journal of Clinical Oncology, 2015
7562 Background: Malignant pleural mesothelioma (MPM) is an aggressive tumor mainly associated with asbestos exposure and characterized by a poor outcome (median overall survival (mOS) < 1 year), t...
Francesco Grossi, Anna Truini, Ernest Nadal, Carlo Genova, Erika Rijavec, Giulia Barletta, Federica Biello, Simona Coco, Maria Giovanna Dal Bello, Irene Vanni, Angela Alama, David G. Beer   +11 more
openaire   +1 more source

Prognostic Signature for Pancreatic Cancer: Are We Close?

Future Oncology, 2009
Pancreatic cancer is a deadly disease with an annual incidence rate nearly equal to its mortality rate. Incremental improvement in outcome has been seen in the last 25 years, illustrating the critical need for novel approaches and intensive research investment.
openaire   +2 more sources

Prognostic and Predictive Role of Genetic Signatures

2017
A robust body of evidence, initiated by the seminal studies of Dr. Perou’s group at the dawn of the new millennium [1, 2] and repeatedly confirmed over the following decade, has convincingly demonstrated that breast cancer (BC) is a heterogeneous disease further classifiable in at least four molecular intrinsic subtypes (luminal A and B, HER2 enriched,
Giancarlo Pruneri, Francesca Boggio
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Prognostic Predictors: Genetic Signatures, Adjuvant!, and PREDICT

2019
Predictive factors are responsible in determining the recurrence risk and death related to cancer and therefore to stablish the natural history of the disease regardless the treatment performed. Predictive factors are those that determine the outcome to a treatment.
Marcelo Rocha Cruz, Antônio Carlos Buzaid   +1 more
openaire   +1 more source

Prognostic Gene Signatures in Skin Cancer

2023
Colette Pameijer, Wen-Qing Li, Gagan Chhabra   +2 more
openaire   +1 more source