Results 111 to 120 of about 35,448 (299)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Energiaigényességi pályák: nemzetközi összehasonlítás = Trends in Energy-Intensiveness: an international comparison [PDF]
A szerző közös felületen ábrázolja az egyes országok energiafogyasztását, valamint GDP-ben mért fejlettségét. Szembetűnő, hogy a szocialista országok fejlettségük alapján az európai országok trendvonalához képest két-háromszoros energiafelhasználással ...
Fleischer, Tamás
core
The Expression of the Claudin Family of Proteins in Colorectal Cancer
Claudins (CLDN1–CLDN24) are a family of tight junction proteins whose dysregulation has been implicated in tumorigeneses of many cancer types. In colorectal cancer (CRC), CLDN1, CLDN2, CLDN4, and CLDN18 have been shown to either be upregulated or ...
Kristin E. Cox +5 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A Distributed Approach to System-Level Prognostics [PDF]
Prognostics, which deals with predicting remaining useful life of components, subsystems, and systems, is a key technology for systems health management that leads to improved safety and reliability with reduced costs.
Bregon, Anibal +2 more
core +1 more source
A REVIEW: PROGNOSTICS AND HEALTH MANAGEMENT IN AUTOMOTIVE AND AEROSPACE
Prognostics and Health Management (PHM) attracts increasing interest of many researchers due to its potentially important applications in diverse disciplines and industries.
Van Duc Nguyen +6 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
ADEPS: a methodology for designing prognostic applications [PDF]
Prognostics applications predict the future evolution of an asset under study, by diagnosing the actual health state and modeling the future degradation.
Aizpurua, Jose Ignacio +1 more
core

