Results 61 to 70 of about 15,777,155 (294)
MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou +9 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Научный вестник МГТУ ГА, 2016 The article emphasises that introduction of new generation aircrat into a domestic market of aviation transportation requires altering traditional methods and procedures to train inspectors of flight safety supervision. At present it is not sufficient to
L. G. Bolshedvorskaya
doaj
The influence of the authorial program on indexes of physical development of overweight senior pupils in mountain schools of the Carpathian region. [PDF]
Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2011 Influence of the authorial program is examined on the indexes of physical development of overweight senior pupils. The changes of separate indexes of physical development of overweight senior pupils that occupied on the authorial program are shown.
Mukutun L.M
doaj
The Effects of Skill Lab Programs in Training of Neurosurgery Residents
Iranian Journal of Neurosurgery, 2021 Background and Aim: Nowadays, surgical educations and training experience new problems. Legal issues and patients' rights are a matter of concern in educational hospitals.
Amir Saied Seddighi +6 more
doaj
The Amur Expedition in 1910: An Experience of Statistical and Economic Surveys of Cossack and Peasant Farms in the Amur Region [PDF]
Prostranstvennaâ Èkonomika, 2010 The article views an experience of organizing statistical and economic surveys of Cossack and peasant farms in the Amur Region during the Amur expedition in 1910.
Elena Lvovna Lee +1 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Современные информационные технологии и IT-образование, 2020 A database containing Perl programs, descriptions and a list of keywords for each program was developed. According to these keywords, the user can determine the area of interest which includes the program, he is looking for.
Anna Kulikovskaya +2 more
doaj +1 more source