Results 101 to 110 of about 34,628,233 (409)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Optimized Data-Flow Integrity for Modern Compilers

open access: yesIEEE Access
Non-control-data attacks are those attacks that purely target and modify the non-control data of a program, such as boolean values, user input or configuration parameters, and leave the control flow of a program untouched. These attacks were considered a
Irene Diez-Franco   +2 more
doaj   +1 more source

Selecting Refining and Evaluating Properties for Program Analysis

open access: yes, 2003
This research proposes and evaluates techniques for selectingpredicates for conditional program properties—thatis, implications such as p ) q whose consequent must betrue whenever the predicate is true.
Ernst, Michael D., Dodoo, Nii, Lin, Lee
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Survey on Verification of Security and Safety in IoT Systems

open access: yesIEEE Access
Internet of Things (IoT) has been rapidly growing in the past few years in all life disciplines. IoT provides automation and smart control across various domains, including home automation, healthcare, and automotive.
Lobna Abuserrieh, Manar H. Alalfi
doaj   +1 more source

Combining the logical and the probabilistic in program analysis

open access: yesMAPL@PLDI, 2017
Conventional program analyses have made great strides by leveraging logical reasoning. However, they cannot handle uncertain knowledge, and they lack the ability to learn and adapt. This in turn hinders the accuracy, scalability, and usability of program
Xin Zhang, X. Si, M. Naik
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Dynamic Program Analysis and Visualized Learning System in University Programming Courses

open access: yesEngineering Proceedings
To correspond to the advancement of technology, programming has become an indispensable course in university curricula. However, students easily become confused by the rules governing program execution or by complex logical structures.
Pei-Wen Lin, Shu-Han Yu, Chien-Hung Lai
doaj   +1 more source

LmPa: Improving Decompilation by Synergy of Large Language Model and Program Analysis

open access: yesarXiv.org, 2023
Xiangzhe Xu   +8 more
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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