Results 101 to 110 of about 3,385,810 (267)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Evaluation of Ethanol Grade on the Robustness of Acid Number Determination in Fish Oil

open access: yesIndonesian Journal of Chemical Analysis
The robustness evaluation of the acid number analysis method in fish oil was carried out to see the effect of the type of ethanol used as a solvent in the titration process. The types of ethanol used in this study were pro analysis grade, pharma and food
Tri Esti Purbaningtias, Sandy
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

In Vitro Biological Evaluation of Titanium Implants Anodized With Aqueous Extract of Psidium guajava and Conventional Electrolytes

open access: yesInternational Journal of Biomaterials
Titanium implants can release ions that damage cells. Anodization creates a protective oxide layer, but conventional acid methods raise environmental and safety concerns.
Felipe Gustavo Dias   +7 more
doaj   +1 more source

Identifying and Mitigating Gender Bias in Social Media Sentiment Analysis: A Post-Training Approach on Example of the 2023 Morocco Earthquake

open access: yesInformation
Sentiment analysis is a cornerstone in many contextual data analyses, from opinion mining to public discussion analysis. Gender bias is one of the well-known issues in sentiment analysis models, which can produce different results for the same text ...
Mohammad Reza Yeganegi   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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