Results 101 to 110 of about 9,895,757 (306)

Uncertainty in soil data can outweigh climate impact signals in global crop yield simulations

Nature Communications, 2016
Global gridded crop models are increasingly used to assess climate change impacts on food production. Here, the authors assess crop yield uncertainty associated with soil data input, reporting that soil type strongly influences yield estimates, and may ...
Christian Folberth, Rastislav Skalský, Elena Moltchanova, Juraj Balkovič, Ligia B. Azevedo, Michael Obersteiner, Marijn van der Velde   +6 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Understanding the origin of Paris Agreement emission uncertainties

Nature Communications, 2017
The pledges put forward by each country to meet the goals of the Paris Agreement are ambiguous. Rogeljet al. quantify the uncertainty arising from the interpretation of these pledges and find that by 2030 global emissions can vary by −10% to +20% around ...
Joeri Rogelj, Oliver Fricko, Malte Meinshausen, Volker Krey, Johanna J. J. Zilliacus, Keywan Riahi   +5 more
doaj   +1 more source

New strategic platform [PDF]

, 2016
In an ever-changing world, each and every entity must continue to develop and adapt to its external environment and the demands placed upon it. The PRGA Program is no exception.
CGIAR Systemwide Program on Participatory Research and Gender Analysis for Technology Development and Institutional Innovation
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Analyzing the use of fact-checking tools in disaster-risk reduction in Europe through the lens of the heuristic-systematic model

Scientific Reports
Journalists, emergency responders, and the general public facing natural and anthropogenic disasters frequently disseminate emergency information via social media.
Nadejda Komendantova, Tahereh Zobeidi, Masoud Yazdanpanah   +2 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Identifying predictive features of Clostridium difficile infection recurrence before, during, and after primary antibiotic treatment

Microbiome, 2017
Background Colonization by the pathogen Clostridium difficile often occurs in the background of a disrupted microbial community. Identifying specific organisms conferring resistance to invasion by C.
Sepideh Pakpour, Amit Bhanvadia, Roger Zhu, Abhimanyu Amarnani, Sean M. Gibbons, Thomas Gurry, Eric J. Alm, Laura A. Martello   +7 more
doaj   +1 more source

HOST structural analysis program overview [PDF]

Hot-section components of aircraft gas turbine engines are subjected to severe thermal structural loading conditions, especially during the startup and takeoff portions of the engine cycle.
Thompson, Robert L.
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source